So, I've played The Amazing Spiderman game, liked it, until the ending. It got me thinking - Smythe there gos some sick moves with his tech. Giant scorpion robots, flying squids, tunneling snake-bots. Man, that's got to be expensive... So watching all this glowy flying thingies got me thinking - why the hell he and Iron Man never clashed? (on my memory at least). They're both brilliant engineers and apparently can just fart out convinient gadgets as plot requires.

So let's consider this situation - let's pretend for a second ASM and Avengers do share Cinematic Universe. Smythe's snake Spider-Slayer trashes the cityblock and Tony actually gets off his couch and helps Peter to put it down for good. From this point on this is on. Alistair is aware that rich playboy, philanthropist and, oh yea, a genius in superpowered armor is out to get him. Tony is aware that renegade OsCorp robotics expert literally expropriated conveyor robot assemblers and builds new dangerous stuff non-stop.

For convenience sake let's assume that's Movie-Stark and, since the game was a tie-in, that version of Smythe doesn't have Ultimate Slayer enhancements.