Genos alone can kill Itachi, nulls all of his Genjutsu and has way more Physicals and firepower.
Most of the S Class can also stomp him, the Top tiers can all fight Dragon Disasters like Carnage Kabuto who scale to at least City/Mountain Level+.
Itachi is also vastly inferior to every S Class minus King and possibly Zombieman in terms of Physicals and durability, even the weakest Tank Top and Puripuri Prisoner dwarf Itachi in H2h.
Adding tatsumaki is pure spite, she can crush itachi and turn him into a baseball in a matter of moments, even a Demon Class disaster like Hundred eye Octopus who is probably 10000s of times stronger physically than Itachi got compressed into a ball shape
Those that can solo:
1. Tatsumaki -> Low Diff
2. Bang -> Low to Mid Diff, strong enough to crush the defense of Dragon Disaster Centipede who could easily tank Genos Attacks.
3. Metal Bat -> this one can go either way, Metal bat can get stronger in battle and be strong enough to match a Dragon Disaster but his starting/base stats arent that strong.
4. Atomic Samura -> Low Diffw
5. Child Emperor -> Low to Mid Diff
6. Drive Knight -> Low to Mid Diff
7. Superallow Darkshine -> low diff on 99% of scenarios, none of itachi attacks would probably scratch Darkshine, only NLF totsuka blade can do something.
8. Metal Knight- spam missiles and technological weapons.
Itachi gets crushed all rounds with low diff.
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