There's Going To Be A Big Mutant Reunion In Second Coming

Second Coming is almost here. You can't have a big X-event without a gathering of mutants. Everyone seems to be vying for the spotlight.  Check out the latest teaser from Marvel: 

When you see all these mutants together, it makes an easy target for their enemies. If you want to take out all the X-Men, they're right there waiting for you. 
 
What will this major catastrophe be that they need to face? Will the combine strength of all these mutants be enough to take it on?