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Dr. Karla Sofen is a founding member of the Thunderbolts and former member of the Masters of Evil. She has flirted with both sides of the law in Norman Osborn's Avengers as Ms. Marvel. She's a control freak with nearly limitless power granted her by moonstones, hence her codename.
Ares is the son of Zeus and the Olympian God of War. After years of fighting against The Avengers, Thor, and mostly his own brother Hercules, Ares joined the ranks of the Avengers. He was a member of Tony Stark's official Avengers team and later Norman Osborn's Dark Avengers. After he attacked Osborn for tricking him in starting Siege on Asgard, he was stopped and killed by the Sentry.
The Venom symbiote originally bonded with Peter Parker, AKA Spider-Man, during his adventure in the first Secret Wars on the Beyonder's planet called Battleworld. Initially, he thought the symbiote was just an attire. However, upon his discovery, he rejected it because he realized that it was sentient. Since then, the symbiote has bonded with several other hosts, including Eddie Brock, Angelo Fortunato, Flash Thompson, Ann Weying, and even Carol Danvers. Currently, its host is Eddie Brock.
A deadly killer for hire capable of using practically anything as a lethal projectile weapon with flawless accuracy and deadly force. He is one of the most psychotic and sadistic characters in Marvel and serves as one of Daredevil's most dangerous foes.
MacDonald "Mac" Gargan was a failing private investigator that was turned into the Scorpion with financial help from J. Jonah Jameson. He became a host of the Venom symbiote and was part of Norman Osborn's Dark Avengers. After the US Government took the symbiote, he became The Scorpion once again.
Daken is Wolverine's long lost son, torn from his mother's womb by the dark figure Romulus. Raised with a warped view on his father's "abandonment" and his mother's murder, Daken was left holding a grudge.
The amoral industrialist Norman Osborn was transformed by an experimental serum into the maniacal Green Goblin, and has endured over the decades as Spider-Man's most dreaded archenemy. Osborn is known for being the killer of Gwen Stacy, the architect of the Clone Saga, and the one-time director of S.H.I.E.L.D.
Agent McGill works for H.A.M.M.E.R. and is stationed in Avengers Tower.
M.O.D.O.K. is an acronym for Mental Organism Designed Only for Killing. He has a plethora of psychic powers, which he used to take control of A.I.M.
Thaddeus "Thunderbolt" Ross is former U.S. military general. He is father of Bruce Banner's love Betty Ross and was archenemy of the Incredible Hulk. Ross made a deal with villains to be transformed into a Hulk himself. As the ruthless and cunning Red Hulk, he attempted to destroy his nemesis and take control of the country before seeking redemption as an Avenger. After leaving the team, he formed his own group of Thunderbolts with other Anti-Heroes. He was recently depowered by Doctor Green.
Johnny Blaze, a motorcycle stuntman, became bound to the Spirit of Vengeance known as Zarathos after making a deal with Mephisto to spare the life of his surrogate father. With the power to control hellfire and to inflict pain on those he deems evil with his Penance Stare, Johnny seeks vengeance as Ghost Rider.
Cyber is a mutant and an enemy of Wolverine and the X-Men. He is also well known throughout the criminal underworld, where he often hires himself out as a special enforcer, he is currently using the Hornet identity.
Wade Wilson is a former test subject of the Weapon X program, where he received his regenerative healing factor through the scientific experiments conducted upon him. A prominent enemy, ally and later, member of X-Force. He's famous for breaking the Fourth Wall.
Yukio is a Ronin (masterless Samurai). She is an ally of the X-Men, specifically Wolverine and Storm. She is part of Professor X's secret network of humans and mutants known as the Mutant Underground.
Daughter of Sgt. Doolin, a war buddy of Wolverine who was killed in the Canadian wilderness. She blamed Wolverine and the Hunter in Darkness for his death.
Noh-Varr was the youngest member of a Kree diplomatic team that was blown out of the sky after reaching Earth. Noh-Varr was the only one who survived. He then vowed vengeance on all mankind but was later tasked with protecting them in the name of the Kree, becoming Captain Marvel and later the Protector. After being forced out of the Avengers, he would then become a part of the Young Avengers.
Moses became President of Deterrence Research Corporation, which is the world's independent weapons manufacturing firm. This would lead to several conflicts with heroes. Moses Magnum is an arms dealer, terrorist, and a supervillain
A minor thug and assassin who is proficient in the use of edged weapons. Brother of the hero Diamondback.
Black Talon derives his power from the mystic Voodoo arts. He can raise zombies and control them at will.
A super-strong mercenary and member of the Serpent Society.
Aryan is a white supremacist enemy of Wolverine and his son Daken
Cottonmouth is a vicious member of the Serpent Society with the ability to unhinge his jaw. With a row of steel teeth, he enjoys biting the heads off of his victims.
Former call girl and member of many organizations, most notably the Serpent Society and B.A.D. Girls Inc.
Bushmaster is a human being with cybernetic arms as well as a cybernetic serpent's tail in place of his legs after his limbs were destroyed in an accident.
Believed dead near the end of World War II only to have been found and brainwashed by the Soviets for the next 50 years, Captain America's former sidekick now continues to defend his country from the shadows against those who would threaten it as legendary spy and assassin, the Winter Soldier. He became the new Captain America to honor his friend Steve and he joined the Avengers. When Steve returned as Captain America, Bucky took on the identity of the Winter Soldier once again.
Milo Gunderson was a mentally challenged mutant with super-strength. Taking advantage of his simple mind, Cyber gained control of his body.
Bunny Brennan was a girl Daken had a relationship with, although he was just using her.
An extremely violent boxer turned criminal, Loki bestowed his powers upon him, and he was transformed into the Absorbing Man, granting him powers to absorb any material and take on its properties. He is the on-again-off-again husband of Titania, and an enemy of Thor and Hulk.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
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