It's an Inferno tie-in and it's producing Spidey's greatest nightmare yet! In a New York City gone mad, where--how--can Spidey find his wife? His desperate search plunges him into a horror-filled city sewers--and on a collision course with the demonically transformed Hobgoblin!
A day has passed since the previous issue. Everything is still out of control in the city and Hobgoblin is not happy with the effects of what N'astirh has done to him. He spots Spidey swinging through the city and goes after him.
Spider-Man goes to the studios where MJ had a modelling assignment earlier in the day. She and the rest of the crew are down in the sewers after trying to escape when demons attacked the studio.
Daily Bugle reporters Ben and Joy are now fully distracted from the Kingpin story as they help out in the Bugle offices which have been nearly destroyed by demonic attacks.
Glory and Eduardo are still hanging out together and they are out on the streets evading burning overturned cars and possessed New Yorkers. Glory thinks they should take shelter in the Daily Bugle building but Eduardo assures her that he can keep her safe himself.
They make their way through a trashed warehouse but retreat to an alley when they are attacked by a forklift that has come to life. Eduardo pushes Gloria aside to protect her. Then, he grabs a handy metal pipe, takes a prodigious leap and uses the pipe to stab the forklift. The forklift explodes and burns. Glory observes this super-human feat and realizes that she knows nothing about Eduardo but his name. It is enough. She loves him. Eduardo returns to her and, amid all the devastation, he and Glory stop briefly and kiss.
Harry is out in Queens, and decides to check on May for Pete.
Hobgoblin attacks Spidey in the sewers. With his new powers, he is faster and stronger than before. Elsewhere in the sewers, the slime at the bottom has come to life and is attacking MJ and the photoshoot crew.
Hobgoblin and Spidey are fighting with Hobby well on top. MJ and her crew stumble across them though and MJ manages to set Hobby on fire, giving Spidey the upper hand. The ceiling begins to fall in as Spidey gets everyone to safety. Hobgoblin is seemingly trapped.
Out in Queens, May resolves to go to Manhattan.