Weasel attended the same college Peter Parker did. If not for a time traveling Deadpool posing as Peter Parker and taking Weasel on a drinking binge, Weasel's life as an A+ student wouldn't have been ruined, ending up with him as a loser specializing in technology.

He eventually became a weapons dealer and partner to Deadpool, as well as a somewhat reluctant friend.

He once took control of a Hydra base, becoming their leader and inventing the "Penetrator," a device that provided much innuendo and could also teleport people anywhere. He equipped all of the Hydra agents with one, and had the devices programmed to send them away. Wolverine attacked the base, not realizing that Weasel was just executing an elaborate plan. Wolverine damaged the armor, and Weasel quickly tried to explain that it was called the penetraitor armor, and that he was trying to remove the agents from the base. The damaged penetrator then sent Weasel, Deadpool, and Bob, Agent of HYDRA, tumbling through space and time, although Weasel was separated from the other two.

Video Games

Weasel appears in Marvel: Ultimate Alliance. Here's short recap of him from the video game:

Hero's Hacker

After Weasel meets Deadpool, and Deadpool becomes a part time agent for S.H.I.E.L.D., Weasel follows Deadpool everywhere. After the larger group of heroes becomes suspicious of Nick Fury's assistant Natasha, one of the black widows, all the heroes call upon Weasel's skills to secretly get information on S.H.I.E.L.D. and Natasha. But Weasel needs the heroes to get him passwords, and other information. When S.H.I.E.L.D. is forced to move their HQ, Deadpool tells Weasel where to find the new HQ, so he can still help them. However, S.H.I.E.L.D. found out that someone was hacking into their system. They then raided Weasel's HQ, which caused him to find a new safe place to stay, which ended up being Xavier's school for mutants.