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A brilliant botanical biochemist, Pamela Isley is a fervent eco-terrorist out to save the world's plant life by any means necessary. She often finds herself at odds with Batman, though they have, on occasion, fought on the same side.
Bruce Wayne, who witnessed the murder of his billionaire parents as a child, swore to avenge their deaths. He trained extensively to achieve mental and physical perfection, mastering martial arts, detective skills, and criminal psychology. Costumed as a bat to prey on the fears of criminals, and utilizing a high-tech arsenal, he became the legendary Batman.
Neron is a fallen angel of Hell, a Devilish being of great power.
Edward Nigma is a villain obsessed with riddles, puzzles, and brain teasers, who took the alias of the Riddler to commit crimes. Riddler frequently tries to outsmart Gotham's hero Batman, but is always defeated by the Dark Knight.
Formerly the D.A. of Gotham City, Harvey Dent was an ally of Batman and Commissioner Gordon until he had acid thrown onto the left side of his face by a mob boss, scarring him for life. The incident drove Harvey insane and he became Two-Face, obsessed with chance and always carrying a double-headed coin, which he flips to determine his every decision.
A delusional serial killer that feeds on people's hearts to survive and has the psychic ability to make people see him as someone else.
Amygdala is frequent inmate of Arkham Asylum, he has no amygdala resulting in him having inhuman rage and super human strength. He was once a resident in Dick Grayson's apartment building while working at Lockhaven Prison.
Mr. Zsasz is a serial killer with no regard for human life. He carves a mark into his skin for every life he takes, slowly covering his entire body in scars.
The head of Arkham Asylum and recently he has been operating secretly as Black Mask, until he was captured and thrown into his own Asylum.
An Arkham inmate, belived that the ghost of Benjamin Franklin drive him to his crimes.
Kryppen the Poisoner is a madman in Arkham Asylum who used to poison all of his victims.
A man who believed himself to be the historical Julius Caesar. He was also one of a henchman of Maxie Zeus.
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