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Part of an ancient alien race, Uatu the Watcher is an incredibly powerful being that has sworn never to interfere with the happenings of the Universe, only to watch, yet he has broken this oath several times.
Reed Richards of the Ultimate Universe (Earth-1610). Once the leader of that universe's Fantastic Four. He is now known as Maker and a version of him resides on every universe in the multiverse after the events of Secret Wars.
Spider-Woman of Earth-1610. She is a female clone of Peter Parker - Spider-Man. Despite the circumstances of her upbringing, she is determined to be a force of good. She works for SHIELD, and is a recurrent member of the Ultimates.
Lori Baumgartner is the brains behind Bombshells mother and daughter team.
Lana Baumgartner is known as Bombshell with her mother when they rob banks. She, along with Miles Morales where transported from the Ultimate Universe into the prime Marvel Universe 616 after Secret Wars.
Camellia is The Chameleon's sister on Earth-1610. Like her brother, Camellia is a shape-shifting thief who holds little to no regard for human life and is willing to do whatever it takes to get what she and her brother want.
Former call girl and member of many organizations, most notably the Serpent Society and B.A.D. Girls Inc.
Asp has the ability to discharge "venom bolts" that can paralyze or even kill someone instantly.
After encountering the Kree hero Captain Marvel, Carol Danvers was accidentally subjected to otherworldly radiation that transformed her into a superhuman warrior. Calling herself Ms. Marvel, she established herself as one of the most powerful and prominent heroes and respected member of the Avengers. She has now adopted the mantle of Captain Marvel for herself.
A super-strong mercenary and member of the Serpent Society.
Death Adder was a mute killer who was a member of the Serpent Society. He was killed by the Scourge of the Underworld, but later was brought back by The Hood in order to eliminate the Punisher. Most recently Death Adder joined Crime-Master's Savage Six.
Mary Jane Watson is an actress and a major love interest of Peter Parker aka Spider-Man. They have had a long and dramatic on-and-off-again relationship. She's one of the few people who know who he is and still supports him as a close friend and confidante.
In the Ultimate Universe, Kenny McFarlane is friends with Peter Parker and Mary Jane Watson. He was also friends with Flash Thompson and developed a crush on the popular transfer student, Kitty Pryde.
Seductive snake charmer and, notably, the first villainess Spider-Man ever faced.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
A former investigative journalist for the Daily Bugle and current owner of the newspaper Front Line who uses his friendships with Daredevil and Spider-Man to get information on criminals.
Dmitri Smerdyakov, AKA Chameleon, was first member of an inexperienced Spider-Man's rogue's gallery. The Chameleon is an elite spy and a master of disguise, using a variety of masks, technology, and other inventive techniques to flawless mimic the appearance and mannerisms of virtually anyone. Although he has been revealed to be the half-brother of Kraven The Hunter, the face behind his trade-mark white mask – worn even beneath his other masks – has never been seen.
Kitty Pryde (a.k.a. Shadowcat) is a mutant gifted with the ability to become intangible and phase her entire body through solid material. A talented prodigy, she became the poster child of the X-Men; eventually reaching maturation and becoming the team's current leader.
A scrappy, rebellious orphan, Rick Jones stumbled into the test site for the Gamma Bomb and inadvertently caused Bruce Banner to be caught in the blast that transformed Banner into the Hulk. Rick became the Hulk's closest confidant, a member of the Avengers, and a friend and sidekick to multiple heroes. Rick eventually became an immortal gamma mutate and has undergone multiple transformations.
Susan Storm is a founding member of the Fantastic Four and later the Future Foundation. She is able to create invisible force fields of any shape she conceives and able to turn herself and anything she's in contact with invisible. Sue is the wife of Reed Richards and the mother of their children, Franklin and Valeria.
The second most powerful member of the Fantastic Four and the younger brother of Sue Richards. Due to an accident caused by cosmic radiation in space, he can manipulate fire, turn his entire body into it and fly. While Johnny is known for his impetuous and sometimes reckless nature, he is also a loyal friend and fearless hero.
Ben Grimm, better known as the Thing, is the original quintessential tough-guy of the Marvel Universe. But, because of his transformation, he's also the tragic member of the Fantastic Four. Ben was an ace test-pilot until exposure to intense cosmic radiation mutated him into a rock-skinned monster with immense superhuman strength. Ben's exterior is much harder than stone which gives him a rather gruff disposition; but deep down, he has a heart of gold.
Peter Parker's aunt-by-marriage and one of the most important people in his life.
Flash frequently bullied Peter Parker but was actually Spider-Man's greatest fan. In time, Flash befriended Peter, became a decorated war hero, and eventually joined the Marvel superheroes as a symbiote host, first with Venom and then with Anti-Venom.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
Gwen Stacy was the first true love of Peter Parker. She's best known for her tragic death by being thrown off from the Brooklyn Bridge by the Green Goblin. The Earth-65 version is Spider-Gwen who is a major player in the Spider family.
The youngest member of the original X-Men. Bobby is an Omega-level mutant, although it took some help from Emma Frost to realize this. Bobby's control of ice is vast; he can create shields, clones, spikes, slides and also freeze others. He was recently elected to Krakoa's X-Men
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