A street cable car holding 59 passengers in San Francisco is struck by a mysterious lightning bolt that imbues each passenger with a super power, changing them into Ultras. Later at night, a mysterious woman with powers arrives at the scene where the lightning bolt struck, causing a commotion with people who were on the cable car and the police. Six strangers from the cable car accident step up to battle the mysterious woman when she attacks the police officers. The mysterious woman takes off into the sky, leaving the six strangers to contemplate that she may have the answers behind the reason they have ultra powers. The six figure out that she must have flew into the only cloud in the sky and decide to follow her using one of the stranger's private jet.