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After a long period of disappearance, The Man-Wolf has reappeared. This time, John Jameson is determined to be rid of his lycanthrope persona for good! Also lending their aid to John in this annual are Curt Connors, Spider-Man, Kristine Saunders, and Jonah Jameson.
An annual bonus features May Parker's photo album that collects images from past significant moments of her life, including her first meeting with Ben Parker, Peter's high school graduation, and his move from May's apartment in Forest Hill.
Other bonuses include a layout of the office for ESU's teaching assistants, a short tale depicting a little practical joke Steve Hopkins plays on Peter, and pin-ups of some of Spider-Man's rogue gallery members including Morbius, Gibbon, Jonas Harrow, and Hammerhead.