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The first person calling himself The Hand was an enemy of the Golden Age Hawkman. Edwin Thayer created a disembodied flying hand that killed his brother and was going to kill his neice Teddy, the sole remaining heir. Edwin Thayer's girlfriend, Sandra undermined his scehme. In his words she was a murderous floozy, ironically he was the murderer.
The second man was Ramon Solomano an enemy of all the Seven Solders of Victory incarnations. Ramon is an old enemy during Greg Saunder's earlier days, as The Vigilante.