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Angel is blind after last issue battle and Cloud is helping him to fly. Johnny Blaze and Roxanne are leaving after helping the Defenders last issues.
In Manhattan Andrea (a girl that is being shown for some issues till now) is with her boyfriend Tony in a bar, while everyone is attacked by a strange guy, who compelled everyone on dancing like crazies. The guy calls himself Spur, and after hitting Tony, Andrea tries to attack him. She is some power girl, because she can hit him very hard, but then he uses his burning vision to escape.
The Defenders decide to go to the Doctor Strange's Sanctuary. There some strange things happen - a soldier named Nancy reveals herself to Cloud as an old friend and calls her sister, also Gargoyle disappears. Valkyrie senses something at Central Park and they go investigate. There they find the Spur doing a strange ritual with compelled people. The Defenders try to beat him up but in vain. Then Andrea shows up and help them, revealing herself as Andromeda.