This is my personal list. I'd like to see what others come up with. Here is what I don't want to see happen in the movie.
-James Gordon killed off: I love the character and it would be cruel punishment for a guy who took a huge a chance and allied himself with guy who dresses as a bat.
-Catwoman/Selina Kyle romantically hook up with Bruce Wayne.
-Talia al Ghul: I know all about the online rumors, but I really don't know what her role would be except to become the mother his son.
-Alfred killed off: Same reason as Gordon except more so as Alfred supported his crazy employer's whims and mentored him.
-The Lazarus pits: They don't seem fit Nolan's gritty reality.
Any other ideas?