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Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Mary Jane Watson is an actress and a major love interest of Peter Parker aka Spider-Man. They have had a long and dramatic on-and-off-again relationship. She's one of the few people who know who he is and still supports him as a close friend and confidante.
Peter Parker's aunt-by-marriage and one of the most important people in his life.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
Harry Osborn is the best friend of Peter Parker, the Amazing Spider-Man. His father is Norman Osborn, a global industrialist and billionaire.
Former New York City Police Department officer and Peter Parker's ex-girlfriend. She was briefly transformed by the Goblin Serum, but has since been returned to normal.
Doctor Octopus is a supervillain originating from Marvel Comics. A former nuclear physicist and atomic researcher, Otto Octavius' life changed forever when one of his experiments went horribly wrong involving his four mechanical appendages used to assist him in his experiments. From then on, Octavius soon after his initial encounter has become one of the most dangerous supervillains in the Marvel Universe.
Betty Brant started as a personal secretary at the Daily Bugle and later became a top reporter. Betty is also one of the many love interests of Peter Parker and ex-girlfriend of Flash Thompson
Editor-in-Chief of the Daily Bugle, and perhaps the best friend to J. Jonah Jameson.
The Venom symbiote originally bonded with Peter Parker, AKA Spider-Man, during his adventure in the first Secret Wars on the Beyonder's planet called Battleworld. Initially, he thought the symbiote was just an attire. However, upon his discovery, he rejected it because he realized that it was sentient. Since then, the symbiote has bonded with several other hosts, including Eddie Brock, Angelo Fortunato, Flash Thompson, Ann Weying, and even Carol Danvers. Currently, its host is Eddie Brock.
During World War II, Steve Rogers volunteered to receive the experimental Super-Soldier Serum. Enhanced to the pinnacle of human physical potential and armed with an unbreakable shield, he became Captain America. After a failed mission left him encased in ice for decades, he was found and revived by the Avengers, later joining their ranks and eventually becoming the team's leader.
Flash frequently bullied Peter Parker but was actually Spider-Man's greatest fan. In time, Flash befriended Peter, became a decorated war hero, and eventually joined the Marvel superheroes as a symbiote host, first with Venom and then with Anti-Venom.
Ben Grimm, better known as the Thing, is the original quintessential tough-guy of the Marvel Universe. But, because of his transformation, he's also the tragic member of the Fantastic Four. Ben was an ace test-pilot until exposure to intense cosmic radiation mutated him into a rock-skinned monster with immense superhuman strength. Ben's exterior is much harder than stone which gives him a rather gruff disposition; but deep down, he has a heart of gold.
The amoral industrialist Norman Osborn was transformed by an experimental serum into the maniacal Green Goblin, and has endured over the decades as Spider-Man's most dreaded archenemy. Osborn is known for being the killer of Gwen Stacy, the architect of the Clone Saga, and the one-time director of S.H.I.E.L.D.
Mysterio was a formidable foe to Spider-Man. So much so that his arts of illusion were carried on by others after the original Mysterio's death. The original Mysterio, Quentin Beck, has recently returned. The events behind his resurrection are currently shrouded in mystery.
A man who would later take the name of Martin Li, was given an experimental drug which eventually allowed him control of some type of black electrical energy resembling a photographic negative.
Max Modell was the head of Horizon Labs and also the employer and good friend of Peter Parker.
Harry Osborn's fiance who absorbed a unique variation of the Goblin Serum that allows her to shapeshift into a goblin. After losing those powers, she assumed the persona of Queen Cat.
Tony Stark was the arrogant son of wealthy, weapon manufacturer Howard Stark. Tony cared only about himself, but he would have a change of heart after he was kidnapped by terrorists and gravely injured. Pressured to create a weapon of mass destruction, Stark instead created a suit of armor powerful enough for him to escape. Tony used his vast resources and intellect to make the world a better place as The Invincible Iron Man. Stark's super hero identity led him to become a founding member of the Avengers.
A police officer in New York. Doesn't have faith that Spider-Man is a good guy.
Dmitri Smerdyakov, AKA Chameleon, was first member of an inexperienced Spider-Man's rogue's gallery. The Chameleon is an elite spy and a master of disguise, using a variety of masks, technology, and other inventive techniques to flawless mimic the appearance and mannerisms of virtually anyone. Although he has been revealed to be the half-brother of Kraven The Hunter, the face behind his trade-mark white mask – worn even beneath his other masks – has never been seen.
The Kingpin is a supervillain originating from Marvel Comics. The self-proclaimed kingpin of crime, Wilson Fisk is one of the most prominent figures of organized crime in the United States. He is the king of mobsters, controlling organized crime on the East Coast with an iron fist. Kingpin is a major enemy of superheroes Spider-Man and Daredevil.
One of Spider-Man's most dangerous enemies, the electric human dynamo known as Electro has constantly been a major threat for the Amazing Spider-Man.
A former investigative journalist for the Daily Bugle and current owner of the newspaper Front Line who uses his friendships with Daredevil and Spider-Man to get information on criminals.
A journalist who worked at the Daily Bugle along with Peter Parker and after Civil War in Front Line newspaper. She seems to like sarcastic humor and Peter is usually the joke.
Reed Richards, also known as Mr. Fantastic, is the leader of the Fantastic Four. He can stretch his body to great distances due to his exposure to cosmic rays while in space. He is also considered to be one of the smartest men alive, using his brain to explore alternate dimensions and save the world alongside his family from science-based threats.
Rumor monger and scandal sheet printer, Dexter Bennett became the latest owner of the Daily Bugle after a hostile buyout of long-time owner J. Jonah Jameson.
Former cat burglar Felicia Hardy became a crime fighter when she became romantically attracted to and involved with Spider-Man. Felicia has the ability to instill "bad luck" around others - this comes in handy when fighting crime!
Kaine was the first clone of Spider-Man created by the Jackal. He was suffering from clone degeneration and became an assassin and spent years tormenting his clone brother, Ben Reilly. He has since taken up the mantle his now dead brother as the new Scarlet Spider.
A long-lived mutant with the rage of a beast and the soul of a Samurai, James "Logan" Howlett's once mysterious past is filled with blood, war, and betrayal. Possessing an accelerated healing factor, keenly enhanced senses, and bone claws in each hand (along with his skeleton) that are coated in adamantium; Wolverine is, without question, the ultimate weapon.
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