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The Wall-Crawler confronts the Kingpin! Spider-to-man! Is this their final battle?
By J. Michael Straczynski and Ron Garney.
Plus: Eddie Brock is dying of cancer, but he cannot escape venom!
By Roberto Aguirre-Sacasa and Lee Weeks.
Also: The race is on to save Flint Marko! But will Spidey and Sandman be in time?
By Peter David and Todd Nauck.
Includes material reprinted from: Amazing Spider-Man #542, Sensational Spider-Man #38 and Friendly Neighborhood Spider-Man #19