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When a pounding Spider-Sense headache leads Spider-Man to the comatose body of his biggest, toughest foe, he realises that something — or someone — can indeed stop the Juggernaut! But who? How? And who are they coming for next? Can Spider-Man find out before it's too late? And will Peter Parker ever get to have dinner with Carlie Cooper?

Plus, discover the secrets of the origins of one Spidey’s deadliest foes, the master of illusion and nightmares… Mysterio!

Also, Curt Connors has played a tricky role in the life of Peter Parker – at his best, he’s an ally whom even Spider-Man must keep an eye on. At his worst, he’s The Lizard – a ferocious creature with killer instincts – and Connors’ fine scientific mind to boot. Now, be prepared for The Lizard’s sense-shattering return!

Includes material reprinted from Amazing Spider-Man #627-628 and Web of Spider-Man #4 and 6!

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