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Carrie Bradley was a stockbroker and self-defense instructor. She was briefly a neighbor and love interest of the Scarlet Spider.
Otto Octavius' apprentice, who took the title of her mentor after Octavius' death, and has fought Spider-Man many times.
The second and most successful clone of Spider-Man created by the Jackal. A superhero known as the Scarlet Spider, Reilly later replaced Peter Parker for a time as Spider-Man after he found out that all this time he was the original and not Peter. Ben met his ultimate demise in the fight against the Green Goblin which led to Peter becoming Spider-Man once again, after he found out that he is the real Spider-Man after all.
Joe Wade is a man infected with nanobots, that could transform into an armor.
A genius in the fields of biology and genetic engineering as well as a close friend to Ben Reilly, the Scarlett Spider.
Virtual copy of Otto Octavius' mind, and lover of the Second Doctor Octopus - Carolyn Trainer.
A former lover of Doctor Octopus and enemy of Spider-Man who uses virtual reality to become her alter-ego.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Cletus Kassady is a deranged and highly dangerous serial killer and long-time host to the Carnage symbiote.
Mercenary participant in the Great Game and enemy of Spider-Man.
Eddie Brock bonded with the dark alien symbiote after it was discarded by Spider-Man, becoming the first Venom. Later, Brock became Anti-Venom, but the symbiote was lost during the events of Spider-Island. Brock has also been forcibly bonded to the Toxin Symbiote by the Crime-Master, but has reluctantly given it up to stop Carnage. Recently he has re-bonded with Venom.
Norton Fester discovers a small meteor and it gives him superhuman powers when gases from the meteor seeps into his body. He becomes a one man crime wave known as the Looter.
An ambitious reporter for the Daily Bugle. Perhaps most notably, he was the one that first named the Scarlet Spider.
Joystick is a former member of the Masters of Evil and the Thunderbolts. While with the Thunderbolts, it was discovered that Joystick was a double agent working for the Grandmaster and her objective was to steal the Moonstones of Baron Zemo.
Phil Urich, was a hero who, somewhere along the line, began thinking the universe was against him, leading to a psychotic break. Formerly taking up the mantles of Darkhawk, Green Goblin and Hobgoblin, Urich is now known as the Goblin Knight.
Carnage is the offspring of the alien symbiote Venom. It bonded with the crazed serial killer, Cletus Kasady, thus creating one of Spider-Man's most murderous, brutal, and lethal adversaries.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
The Venom symbiote originally bonded with Peter Parker, AKA Spider-Man, during his adventure in the first Secret Wars on the Beyonder's planet called Battleworld. Initially, he thought the symbiote was just an attire. However, upon his discovery, he rejected it because he realized that it was sentient. Since then, the symbiote has bonded with several other hosts, including Eddie Brock, Angelo Fortunato, Flash Thompson, Ann Weying, and even Carol Danvers. Currently, its host is Eddie Brock.
Doctor Octopus is a supervillain originating from Marvel Comics. A former nuclear physicist and atomic researcher, Otto Octavius' life changed forever when one of his experiments went horribly wrong involving his four mechanical appendages used to assist him in his experiments. From then on, Octavius soon after his initial encounter has become one of the most dangerous supervillains in the Marvel Universe.
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