Character » Superman appears in 18942 issues.
Doctor Bedlam is a master scientist and a being of pure psionic energy. As such he is usually invisible, but can make himself appear in the form of the face he once had.
Scientific from STAR Labs who knows a lot about different dimensions and the multiverse. Her intentions seems to be not totally honest.
A scientist who turned himself into living Kryptonite weapon.
A one shot character from a Justice League of America story during the pre-Crisis universe.
Dr. Jon Osterman was a lowly lab technician, before he was caught in a radioactive particle test. He returned as a god-like superhuman. He is powerful and highly intelligent, yet he grew to become emotionally distant towards people. He is the only superhero with powers in the Watchmen storyline.
Dr. Omen is the Director of the Ministry of Self-Reliance, founder of the Justice League of China, and mother of Kong Kenan - the Super-Man of China.
A mysterious mad scientist working in Metropolis.
Once a researcher working for the betterment of mankind, Neal Emerson became a master of magnetism, and one of the deadliest metahumans on Earth.
She and her twin sister Delia worked in the Task Force Z project.
Dr. Sivana is a scientific genius and is one of Captain Marvel's archenemies. He has also been involved with other heroes in the DC universe, and is regularly seen as part of supervillain team-ups.
Microscopic thug trapped in Batman's bloodstream
Dr. Strangefate is a character from the Amalgam Universe. He is a combination of Doctor Strange/Professor X from Marvel and Doctor Fate from DC. He is the most powerful being in the Amalgam Universe.
A one shot character from a Superman story in the Pre-Crisis universe.
A Manhunter robot sent to Smallville in hopes of getting hold of Superman to make him a Manhunter agent.
He is a Superman and Batman villain from the pre-Crisis universe.
He is an alien warrior that has both fought against and beside Superman.
The Original Count Dracula from Bram Stoker's famous novel. His character has been explored in many comics, including those released by Marvel, DC and many other publishers.
A one shot character from a Superman story during the pre-Crisis universe.
He duplicates the powers of his opponent, creating the illusion that he steals them.
Duran is an Ecological terrorist who uses his magical powers to further his ends.
Durlan is an alien belonging to a shapeshifting race from the planet Durla.
Former Daily Planet mail worker whose wife's death by hands of Titano and reveal of Superman's identity led him to participate in the Daily Planet hostage crisis and shoot Perry White.
Mystical being who gave the Enchantress her powers.
Superman has foiled Wolfingham on several occasions.
Xenophobic tyrant with the ability to siphon the powers of others. Former enemy of the Legion of Super-Heroes, he now was coerced into joining them. It cost him his life.
Superman battled Earthquake when the villain attacked Lex Luthor during his presidential inauguration. Forcing a protesting Superman into saving Luthor.
Mother of all Greek monsters with great power to rival even Zeus.
Echo has power over sound waves, usually causing earthquakes. He is a member of the futuristic Legion of Super-Villains.
Eddie (as Venom) fought Superman in the DC vs Marvel story-arc.
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