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A former spy, professional criminal, and would-be world conqueror, Zebediah "Purple Man" Killgrave is a master mind-controller with violet-hued skin.
The Mandarin is the arch enemy of Iron Man. A remarkable genius with both earthly and extraterrestrial technology, the Mandarin is also an exceptional athlete, swordsman, and martial artist.
M.O.D.O.K. is an acronym for Mental Organism Designed Only for Killing. He has a plethora of psychic powers, which he used to take control of A.I.M.
Temujin is the son of the Mandarin and a member of the Agents of Atlas. Inheriting the Mandarin's powerful rings, Temujin resolved to use his father's resources to bring tranquillity rather than terror to the world.
Dmitri Smerdyakov, AKA Chameleon, was first member of an inexperienced Spider-Man's rogue's gallery. The Chameleon is an elite spy and a master of disguise, using a variety of masks, technology, and other inventive techniques to flawless mimic the appearance and mannerisms of virtually anyone. Although he has been revealed to be the half-brother of Kraven The Hunter, the face behind his trade-mark white mask – worn even beneath his other masks – has never been seen.
Armadillo is a slow-witted man tricked into an inhuman form. He is a criminal by circumstance with few other options in front of him.
Arthur Parks was a brilliant scientist in the field of laser research and design. He became a career criminal using laser technology, and then a being of pure living energy. He is an Iron Man enemy.
An artificial being created by the terrorist group A.I.M. for their plans to assassinate Captain America, it holds a fragment of the Cosmic Cube that serves as its limitless power source, and can copy the powers of any being it wants.
Nightshade is a biochemist with a strong interest in lycanthropy. She uses potions, manipulation and seduction as a means to get her own way and if that doesn't work she also has an army of wolves ready to tear you apart.
Marvin Flumm was one of the first S.H.I.E.L.D. agents to go bad. Using his mental powers under the alias of Mentallo, he turned on S.H.I.E.L.D. along with his partner in crime, the Fixer.
Robert Farrell was a misguided youth, stealing to feed his hungry family. After several confrontations with Spider-Man, he has since learned the errors of his ways.
Puma is a powerful Native-American Werecat. Puma was raised to fight the Beyonder and became an ally to Spider-Man.
Formerly a brilliant scientist, Jonathon Ohnn gained the ability to create teleportation portals when his research went wrong. Turning to a life of crime and adopting the moniker of 'The Spot', Ohnn has since become a semi-frequent adversary to Spider-Man and is oft treated as a less than serious threat despite his capabilities.
Jackson Weele is a villain who travels around through means of a giant wheel he himself created. Hence the name Big Wheel.
Monica Rappaccini was the Supreme Scientist of A.I.M. Her daughter, Carmilla Black, is the Scorpion.
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