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Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
A career criminal, the man known as Rhino has incredible strength and durability. A long-time enemy of Spider-Man and the Incredible Hulk, Rhino isn't particularly malicious, and has tried on various occasions to leave behind his life of crime, but always seems to slide back into old habits.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
Doctor Octopus is a supervillain originating from Marvel Comics. A former nuclear physicist and atomic researcher, Otto Octavius' life changed forever when one of his experiments went horribly wrong involving his four mechanical appendages used to assist him in his experiments. From then on, Octavius soon after his initial encounter has become one of the most dangerous supervillains in the Marvel Universe.
Daily Bugle reporter
Peter Parker's aunt-by-marriage and one of the most important people in his life.
Frank Oliver with his superhuman leaping abilities was the criminal better known as the Kangaroo. After Frank's death, another person named Brian Hibbs took over as the Kangaroo.
One of Spider-Man's most dangerous enemies, the electric human dynamo known as Electro has constantly been a major threat for the Amazing Spider-Man.
The cold, tall and monsterous looking Spider-Man villain who takes pride in his grim and death-like appearance, Lonnie Thompson Lincoln is a criminal enforcer who uses methods of intimidation and murder under the deserving nickname of Tombstone.
Robert Farrell was a misguided youth, stealing to feed his hungry family. After several confrontations with Spider-Man, he has since learned the errors of his ways.
A sentient swarm of spiders that contain the consciousness of Carl King, Peter Parker's high school bully.
Swindled by his business partner out of his equal share of the profits from their company, Adrian Toomes set out for revenge by using a flying harness of his own design. He has however, met defeat several times at the hands of his arch-nemesis, The Amazing Spider-Man.
Daily Bugle Employee and love interest of Spider-Man
When Tombstone was imprisoned in the Cage he was cellmates with Big Ben, Hypno-Hustler, and Rocket Racer.
Formerly a brilliant scientist, Jonathon Ohnn gained the ability to create teleportation portals when his research went wrong. Turning to a life of crime and adopting the moniker of 'The Spot', Ohnn has since become a semi-frequent adversary to Spider-Man and is oft treated as a less than serious threat despite his capabilities.
Former secretary at the Daily Bugle who became one the Thousand's victims. He devoured her and briefly assumed her identity.
The son of Kraven the Hunter, he too is a skilled hunter and tracker. Unlike his father his enhanced abilities are natural and he can talk to animals.
The Hypno-Hustler is a jive-talking black soul Disco singer who uses his goggles and evil boots of death to hypnotize music lovers, alongside his backup band, "The Mercy Killers."
A costume-wearing criminal who is rumored to have cannibalistic tendencies. He went on to join the Masters of Evil and was later appointed to Norman Osborn's Thunderbolts squad to aid them during the Siege of Asgard.
The amoral industrialist Norman Osborn was transformed by an experimental serum into the maniacal Green Goblin, and has endured over the decades as Spider-Man's most dreaded archenemy. Osborn is known for being the killer of Gwen Stacy, the architect of the Clone Saga, and the one-time director of S.H.I.E.L.D.
Timber Hughs is a lover to Alyosha Kravinoff, first seen as a waitress in the Bar With No Name, a supervillain hangout. She was an aspiring actress and Al moved with her to Hollywood where they founded Hunter Productions, their own production company.
The second most powerful member of the Fantastic Four and the younger brother of Sue Richards. Due to an accident caused by cosmic radiation in space, he can manipulate fire, turn his entire body into it and fly. While Johnny is known for his impetuous and sometimes reckless nature, he is also a loyal friend and fearless hero.
Flash frequently bullied Peter Parker but was actually Spider-Man's greatest fan. In time, Flash befriended Peter, became a decorated war hero, and eventually joined the Marvel superheroes as a symbiote host, first with Venom and then with Anti-Venom.
Inspired by the famous novel, Zabo concocted a similar formula. Repeated use of this formula destroyed his sanity and turned him into a savage schizophrenic creature.
Editor-in-Chief of the Daily Bugle, and perhaps the best friend to J. Jonah Jameson.
Betty Brant started as a personal secretary at the Daily Bugle and later became a top reporter. Betty is also one of the many love interests of Peter Parker and ex-girlfriend of Flash Thompson
Costumed villainy and heroism isn't for everybody, Wilbur Day sadly never learned that lesson and found himself being one of the most incompetent villains within the Marvel Universe.
Leap-Frog, former criminal and father of the costumed hero, Frog-Man.
The Kingpin is a supervillain originating from Marvel Comics. The self-proclaimed kingpin of crime, Wilson Fisk is one of the most prominent figures of organized crime in the United States. He is the king of mobsters, controlling organized crime on the East Coast with an iron fist. Kingpin is a major enemy of superheroes Spider-Man and Daredevil.
There has been two persons using the name Matador.
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