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When innocent blood is spilled, a Spirit of Vengeance is born. Dan Ketch transforms into Ghost Rider and nothing will stop him from inflicting pain on all those who have inflicted it on innocent beings. Eventually, Ketch learned to control these transformations. However, it was later revealed that his ancestor was Noble Kale. After some time away, he returned working for Zadkiel.
Detective from Utah who hunted down Kaine
Doctor Octopus is a supervillain originating from Marvel Comics. A former nuclear physicist and atomic researcher, Otto Octavius' life changed forever when one of his experiments went horribly wrong involving his four mechanical appendages used to assist him in his experiments. From then on, Octavius soon after his initial encounter has become one of the most dangerous supervillains in the Marvel Universe.
Editor-in-Chief of the Daily Bugle, and perhaps the best friend to J. Jonah Jameson.
A long-lived mutant with the rage of a beast and the soul of a Samurai, James "Logan" Howlett's once mysterious past is filled with blood, war, and betrayal. Possessing an accelerated healing factor, keenly enhanced senses, and bone claws in each hand (along with his skeleton) that are coated in adamantium; Wolverine is, without question, the ultimate weapon.
The Venom symbiote originally bonded with Peter Parker, AKA Spider-Man, during his adventure in the first Secret Wars on the Beyonder's planet called Battleworld. Initially, he thought the symbiote was just an attire. However, upon his discovery, he rejected it because he realized that it was sentient. Since then, the symbiote has bonded with several other hosts, including Eddie Brock, Angelo Fortunato, Flash Thompson, Ann Weying, and even Carol Danvers. Currently, its host is Eddie Brock.
During an experiment, Dr. Curtis Connors accidentally turned himself into a ferocious reptilian monster who seeks to turn humans into lizards like himself. The Lizard is one of Spider-Man’s oldest and deadliest foes while ironically, his alter ego is a close friend and former teacher of Spidey’s alter ego, Peter Parker.
A genius in the fields of biology and genetic engineering as well as a close friend to Ben Reilly, the Scarlett Spider.
Shocker is a supervillain originating from Marvel Comics. A self-taught engineer, Herman Schultz created a pair of gauntlets that produces shock waves incorporated into a suit that protects him from the impact of of the blasts. He is a recurring foe of the superhero Spider-Man.
An ambitious reporter for the Daily Bugle. Perhaps most notably, he was the one that first named the Scarlet Spider.
Melvin Gooner is a reporter for the Daily Bugle
Police Detective.
A small time criminal that worked his way up to having his own crime family within the Maggia.
A mythological hulking beast that roams the Canadian wilderness, attacking and ingesting those unlucky enough to cross it's path. It is an enemy of various heroes, specifically the Hulk.
The woman named Calypso has a history shrouded in mystery. She was the lover and partner of Kraven until he met his demise, and she carries on his hate for Spider-Man.
The latest in a long line of warriors who wielded the power, Danny Rand is the immortal Iron Fist: protector of the mystical city of K'un Lun. He channels the soul of the dragon Shou-Lao making his fists into powerful weapons. He is among the best, if not the best fighter in the Marvel Universe. He has also been a member of The Defenders and the New Avengers.
A Spirit of Vengeance who mistakenly thought himself to be the ancestor of Danny Ketch and Johnny Blaze, Noble Kale. His identity was later revealed to be an elaborate lie by Mephisto and Blackheart. Noble's true identity remains that of a mysterious Spirit of Vengeance.
Peter Parker's uncle and the father figure whose death was the main inspiration for Peter becoming Spider-Man. Ben Parker taught Peter that with great power comes great responsibility.
A burglar Spider-Man allowed to escape at one point, he would later kill Uncle Ben.
The Spider-Man based doppelgänger created by Magus during the Infinity War.
Terrorism's greatest enemy, Solo is an adept soldier with the ability to teleport himself certain distances. As long as he lives, terror dies.
Elizabeth Allan was a classmate of Peter Parker. She dated and later married Harry Osborn, Peter's best friend. She has a son named Normie Osborn.
Former cat burglar Felicia Hardy became a crime fighter when she became romantically attracted to and involved with Spider-Man. Felicia has the ability to instill "bad luck" around others - this comes in handy when fighting crime!
Buzz was a regular customer to the Daily Grind, a place where Ben Reilly (the Scarlet Spider) used to work. (Buzz is not to be mistaken for the superhero "Buzz" from the Spider-girl comics).
Cletus Kassady is a deranged and highly dangerous serial killer and long-time host to the Carnage symbiote.
Normie Osborn is the son of Harry Osborn and Liz Allan Osborn.
A skill molecular biologist working for Hydra
Carnage is the offspring of the alien symbiote Venom. It bonded with the crazed serial killer, Cletus Kasady, thus creating one of Spider-Man's most murderous, brutal, and lethal adversaries.
Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after realising he was unhappy with his life. He joined the Avengers and later Silver Sable's Wild Pack. Sandman eventually returned to crime after being brainwashed by the Wizard, but sometimes still displays desire to better himself.
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