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Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Mary Jane Watson is an actress and a major love interest of Peter Parker aka Spider-Man. They have had a long and dramatic on-and-off-again relationship. She's one of the few people who know who he is and still supports him as a close friend and confidante.
The second and most successful clone of Spider-Man created by the Jackal. A superhero known as the Scarlet Spider, Reilly later replaced Peter Parker for a time as Spider-Man after he found out that all this time he was the original and not Peter. Ben met his ultimate demise in the fight against the Green Goblin which led to Peter becoming Spider-Man once again, after he found out that he is the real Spider-Man after all.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
Peter Parker's aunt-by-marriage and one of the most important people in his life.
Jason Philip Macendale, former agent of CIA, turned from the first Jack O'Lantern to the second major Hobgoblin and once the host of Demogoblin. He was rebuilt as a cyborg and remained Hobgoblin until the first Hobgoblin who was thought dead returned and killed him.
The second Hobgoblin, Jason Macendale, became possessed by a demon after making a deal with N'astirh for power. When Jason rid himself of the demon he was host to, it became a seperate entity known as Demogoblin.
Betty Brant started as a personal secretary at the Daily Bugle and later became a top reporter. Betty is also one of the many love interests of Peter Parker and ex-girlfriend of Flash Thompson
Cousin of the late Gwen Stacy, and close friend to the Parker family.
Gwen Stacy's uncle, investigator and ally of Spider-Man.
Paul Stacy is Gwen Stacy's cousin.
The amoral industrialist Norman Osborn was transformed by an experimental serum into the maniacal Green Goblin, and has endured over the decades as Spider-Man's most dreaded archenemy. Osborn is known for being the killer of Gwen Stacy, the architect of the Clone Saga, and the one-time director of S.H.I.E.L.D.
A former investigative journalist for the Daily Bugle and current owner of the newspaper Front Line who uses his friendships with Daredevil and Spider-Man to get information on criminals.
Kaine was the first clone of Spider-Man created by the Jackal. He was suffering from clone degeneration and became an assassin and spent years tormenting his clone brother, Ben Reilly. He has since taken up the mantle his now dead brother as the new Scarlet Spider.
One of Spider-Man's most dangerous enemies, the electric human dynamo known as Electro has constantly been a major threat for the Amazing Spider-Man.
Flash frequently bullied Peter Parker but was actually Spider-Man's greatest fan. In time, Flash befriended Peter, became a decorated war hero, and eventually joined the Marvel superheroes as a symbiote host, first with Venom and then with Anti-Venom.
A mobster whom from time to time crossed paths with Ben Reilly, the Scarlet Spider.
Once Michael Morbius was a world-renowned bio-chemist, dying of an unknown blood disease and desperately searching for a cure. He found that cure, but, in turn, it afflicted him with a curse far worse than any possible disease; the curse of the blood-sucking night-beast; the curse of the Living Vampire.
Owner of the Daily Grind coffee shop and former employer of Ben Reilly, the Scarlet Spider.
Swindled by his business partner out of his equal share of the profits from their company, Adrian Toomes set out for revenge by using a flying harness of his own design. He has however, met defeat several times at the hands of his arch-nemesis, The Amazing Spider-Man.
Mysterio was a formidable foe to Spider-Man. So much so that his arts of illusion were carried on by others after the original Mysterio's death. The original Mysterio, Quentin Beck, has recently returned. The events behind his resurrection are currently shrouded in mystery.
Devon is the son of Shirley Washington Lewis and worked at her coffee shop, the Daily Grind.
Anna May Watson is best friends with May Parker and a paternal aunt to Mary Jane Watson. Once the Watsons were neighbors to the Parkers in Forrest Hills.
Created by the military, Deathlok is a Cyborg from the future in the mainstream Marvel Universe, and several alternate universes as well, whom wishes to regain his lost humanity.
Eddie Brock bonded with the dark alien symbiote after it was discarded by Spider-Man, becoming the first Venom. Later, Brock became Anti-Venom, but the symbiote was lost during the events of Spider-Island. Brock has also been forcibly bonded to the Toxin Symbiote by the Crime-Master, but has reluctantly given it up to stop Carnage. Recently he has re-bonded with Venom.
A mob boss allied with Hydra and the Maggia.
Former student and servant to Kraven.
After being bombarded with a massive dose of gamma radiation while saving a young man's life during an experimental bomb testing, Dr. Robert Bruce Banner was transformed into the Incredible Hulk: a green behemoth who is the living personification of rage and pure physical strength.
Grim Hunter is a fictional character by Marvel comics. Grim Hunter is one of the sons of the original Kraven The Hunter.
A long-lived mutant with the rage of a beast and the soul of a Samurai, James "Logan" Howlett's once mysterious past is filled with blood, war, and betrayal. Possessing an accelerated healing factor, keenly enhanced senses, and bone claws in each hand (along with his skeleton) that are coated in adamantium; Wolverine is, without question, the ultimate weapon.
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