This is a question I've been wondering about. Marvel Studios can't use Spider-Man related characters. Like characters that fall under the Spider-Man brand-name such as his villains and supporting characters. However what if they decided to use Spider-Woman. I mean Jessica Drew has no affiliation with Spider-Man aside from somewhat similar powers and the name, so why couldn't they use her to fill the same role? Spider-Woman has always been heavily affiliated with both SHIELD and The Avengers, even working for HYDRA for sometime in the comics, and all of those fall under Disney/Marvel's control.

Perhaps they could have her as a vigilante to begin with? Basically do the same thing Spidey does to start with, but gets drafted into the Avengers at some point? Really I think this would help flesh out their street level heroes more.