Spider-Man story arcs

A time rift causes some of Marvel's most well known heroes to come into existence over three hundred years early, in 1602.

A cross-publisher event of a series of titles put out by both Marvel Comics and DC Comics under the name Amalgam Comics, it blended elements from the two publishers' catalogs.

The world of the Avengers is rocked to its foundation in this cross-over event, leaving the Earth's Mightiest Heroes broken and changing their lives forever.

In the United States, a Super-human Registration Act is passed, which decrees that all Mutants or Super-Humans must register with the government, giving all personal information, as well as powers.

The High Evolutionary attempts to evolve the human race into a more advanced species using various schemes such as eradicating mutants and drugs and setting off a genetic bomb.

The demons of Limbo invades Earth.

Death resurrects Thanos who acquires the six infinity gems and kills half the life in the universe in her honor with the Infinity Gauntlet. Adam Warlock leads Earth's greatest heroes against Thanos.

Carnage, Shriek, Doppelganger, Demogoblin, and Carrion goes on a killing spree in New York.

The culmination of the X-Traitor storyline and the lead in to Heroes Reborn. Onslaught attempted to recreate the world in his image, only to be defeated by the combined sacrifice of Earth's heroes.

Seperation Anxiety is a story taking place in the Marvel universe of Earth-616. It tells the story of five offspring of the Venom symbiote and their hosts and the creation of Hybrid.

Spider-Man: The Other is a story arc on spanned across three major Spider-Man titles.