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Symkarian ruler and leader of a band of mercenaries known as the Wild Pack. More recently she has allied herself with Misty Knight, Paladin and the Heroes for Hire operation.
Cletus Kassady is a deranged and highly dangerous serial killer and long-time host to the Carnage symbiote.
A retired vaudevilian and love interest to Aunt May. He was also friends with Adrian Toomes, the original Vulture.
A former mad, obsessive stalker of Mary Jane Watson.
Styx is a killer for hire and half of the criminal duo Styx & Stone. Styx's touch drains the life from any living thing he touches.
Inspired by the death of his brother, Elias Wirtham set out to right the wrongs that slip through the cracks. He is the vigilante heart of justice. He is Cardiac.
Willie Lumpkin is a fictional supporting character in the Marvel Universe, who is best known as the mailman of the Fantastic Four in their self-titled comic book.
A reporter for the Daily Bugle as well as one-time partner and potential love interest of Peter Parker.
Mary Jane Watson is an actress and a major love interest of Peter Parker aka Spider-Man. They have had a long and dramatic on-and-off-again relationship. She's one of the few people who know who he is and still supports him as a close friend and confidante.
Second half of the criminal duo Styx and Stone who clashed with Spider-Man.
A longtime foe of Iron Man who as a criminal mastermind employed super-villains and organized criminal operations.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Eddie Brock bonded with the dark alien symbiote after it was discarded by Spider-Man, becoming the first Venom. Later, Brock became Anti-Venom, but the symbiote was lost during the events of Spider-Island. Brock has also been forcibly bonded to the Toxin Symbiote by the Crime-Master, but has reluctantly given it up to stop Carnage. Recently he has re-bonded with Venom.
Former pro baseball player who became a known criminal as the Boomerang. After fighting towards some semblance of redemption as a member of the Thunderbolts, he lead the seventh incarnation of the Sinister Six.
A career criminal, the man known as Rhino has incredible strength and durability. A long-time enemy of Spider-Man and the Incredible Hulk, Rhino isn't particularly malicious, and has tried on various occasions to leave behind his life of crime, but always seems to slide back into old habits.
Peter Parker's aunt-by-marriage and one of the most important people in his life.
A former weapons engineer, David Lieberman became the Punisher's weapons supplier for a short time. He was also especially skilled in the use of computers and technology.
When U.S. Marine veteran Frank Castle's family's was murdered for witnessing a mob hit, the man vowed to avenge their deaths and became a one-man army in his personal war against the criminal underworld. With a distinct death's head skull adorning his chest, Frank Castle became the vigilante known as the Punisher.
Flash frequently bullied Peter Parker but was actually Spider-Man's greatest fan. In time, Flash befriended Peter, became a decorated war hero, and eventually joined the Marvel superheroes as a symbiote host, first with Venom and then with Anti-Venom.
The Venom symbiote originally bonded with Peter Parker, AKA Spider-Man, during his adventure in the first Secret Wars on the Beyonder's planet called Battleworld. Initially, he thought the symbiote was just an attire. However, upon his discovery, he rejected it because he realized that it was sentient. Since then, the symbiote has bonded with several other hosts, including Eddie Brock, Angelo Fortunato, Flash Thompson, Ann Weying, and even Carol Danvers. Currently, its host is Eddie Brock.
Former cat burglar Felicia Hardy became a crime fighter when she became romantically attracted to and involved with Spider-Man. Felicia has the ability to instill "bad luck" around others - this comes in handy when fighting crime!
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