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Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Cletus Kassady is a deranged and highly dangerous serial killer and long-time host to the Carnage symbiote.
The Venom symbiote originally bonded with Peter Parker, AKA Spider-Man, during his adventure in the first Secret Wars on the Beyonder's planet called Battleworld. Initially, he thought the symbiote was just an attire. However, upon his discovery, he rejected it because he realized that it was sentient. Since then, the symbiote has bonded with several other hosts, including Eddie Brock, Angelo Fortunato, Flash Thompson, Ann Weying, and even Carol Danvers. Currently, its host is Eddie Brock.
Eddie Brock bonded with the dark alien symbiote after it was discarded by Spider-Man, becoming the first Venom. Later, Brock became Anti-Venom, but the symbiote was lost during the events of Spider-Island. Brock has also been forcibly bonded to the Toxin Symbiote by the Crime-Master, but has reluctantly given it up to stop Carnage. Recently he has re-bonded with Venom.
Carnage is the offspring of the alien symbiote Venom. It bonded with the crazed serial killer, Cletus Kasady, thus creating one of Spider-Man's most murderous, brutal, and lethal adversaries.
John Jameson is an astronaut, a test pilot and for his father J. Jonah Jameson the archetype of a true hero unlike these “masked clowns” like Spider-man. John has also been transformed into a Werewolf-like creature called the Man-Wolf, and was once host to the Carnage Symbiote.
Mary Jane Watson is an actress and a major love interest of Peter Parker aka Spider-Man. They have had a long and dramatic on-and-off-again relationship. She's one of the few people who know who he is and still supports him as a close friend and confidante.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
A founding member of the X-Men, Dr. Hank McCoy is a mutant possessing animal-like strength and agility. Despite being covered in blue fur and resembling a ferocious beast, Hank possesses an astounding intellect and a superb wit. He is currently a key member of X-Force.
Ben Grimm, better known as the Thing, is the original quintessential tough-guy of the Marvel Universe. But, because of his transformation, he's also the tragic member of the Fantastic Four. Ben was an ace test-pilot until exposure to intense cosmic radiation mutated him into a rock-skinned monster with immense superhuman strength. Ben's exterior is much harder than stone which gives him a rather gruff disposition; but deep down, he has a heart of gold.
Beastial who uses the name Wolverine on Counter-Earth, he is not Logan, but does act as a hero on his world. Ally of Spider-Man.
Gwen Stacy was the first true love of Peter Parker. She's best known for her tragic death by being thrown off from the Brooklyn Bridge by the Green Goblin. The Earth-65 version is Spider-Gwen who is a major player in the Spider family.
Reed Richards of Counter-Earth, later escaped to Earth-1123 and became president of the United States. His greatest claim to fame is that he came extremely close to killing the Invisible Girl.
Evolved rat.
Evolved tiger.
Circus bear evolved into humanoid by High Evolutionary.
Sir Ram has the ability to super leap and is easily strong enough to tear through a brick wall can lift about 7 tons and run at about 80 mph
Herbert Wyndham is a geneticist from the 1930s who became obsessed with further evolution experiments which he used on himself. Depending on what he hopes to gain from whatever his current experiments are, he has been a force for the greater good, and for his own dark purposes.
Flash frequently bullied Peter Parker but was actually Spider-Man's greatest fan. In time, Flash befriended Peter, became a decorated war hero, and eventually joined the Marvel superheroes as a symbiote host, first with Venom and then with Anti-Venom.
Dmitri Smerdyakov, AKA Chameleon, was first member of an inexperienced Spider-Man's rogue's gallery. The Chameleon is an elite spy and a master of disguise, using a variety of masks, technology, and other inventive techniques to flawless mimic the appearance and mannerisms of virtually anyone. Although he has been revealed to be the half-brother of Kraven The Hunter, the face behind his trade-mark white mask – worn even beneath his other masks – has never been seen.
Peter Parker's aunt-by-marriage and one of the most important people in his life.
Mysterio was a formidable foe to Spider-Man. So much so that his arts of illusion were carried on by others after the original Mysterio's death. The original Mysterio, Quentin Beck, has recently returned. The events behind his resurrection are currently shrouded in mystery.
Susan Storm is a founding member of the Fantastic Four and later the Future Foundation. She is able to create invisible force fields of any shape she conceives and able to turn herself and anything she's in contact with invisible. Sue is the wife of Reed Richards and the mother of their children, Franklin and Valeria.
The second most powerful member of the Fantastic Four and the younger brother of Sue Richards. Due to an accident caused by cosmic radiation in space, he can manipulate fire, turn his entire body into it and fly. While Johnny is known for his impetuous and sometimes reckless nature, he is also a loyal friend and fearless hero.
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