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In the year 2099, Miguel O'Hara, the head of the genetics department for the Alchemax Corporation becomes the legendary hero know as Spider-Man.
Herbert Wyndham is a geneticist from the 1930s who became obsessed with further evolution experiments which he used on himself. Depending on what he hopes to gain from whatever his current experiments are, he has been a force for the greater good, and for his own dark purposes.
A burglar Spider-Man allowed to escape at one point, he would later kill Uncle Ben.
Elizabeth Allan was a classmate of Peter Parker. She dated and later married Harry Osborn, Peter's best friend. She has a son named Normie Osborn.
Part the "popular crowd" along with Flash Thompson, Brian "Tiny" McKeever, Seymour O'Reilly, and Sally Avril who were often picking on Peter Parker.
As a child, Matt Murdock was blinded by radioactive waste while trying to save an elderly stranger about to get hit by a truck carrying the dangerous material. In turn, his other senses were heightened to superhuman sharpness and he gained a form of "radar sense". By day, he is a successful trial lawyer; but by night, he guards Hell's Kitchen as Daredevil: the Man Without Fear.
After losing his job, Steven Hudak became "Scorcher" to extract his revenge.
Miguel is the mage of the Spider Society
Hulkbunny is the "Hulk" of Larval Earth, home of Spider-Ham. He is also a bunny
A high ranking HYDRA agent whom recruited Jessica Drew for his organization.
Brian "Tiny" McKeever was a friend of Flash Thompson's and part of the popular crowd. Currently, he's the head of security for Empire State University.
Anya Sofía Corazón is a 17 year old super-heroine who originally went by the name Araña and had a symbiotic exoskeleton which emanated from her spider-shaped tattoo. She then lost those powers and instead gained new powers similar to that of Spider-Man. Anya currently goes by the name of Spider-Girl.
Steven Mark Levins is one of several people to call themselves Jack O'Lantern. He has been an enemy to Captain America, Ghost Rider and the Punisher.
The original owner of the Alchemax corporation
A student who became the costumed hero, the Bluebird.
Holo-servant in the future, year 2099
The brother of Miguel O'Hara (aka Spider-Man 2099)
Miguel O' Hara's girlfriend when he first became Spider-Man.
J. Jonah Jackal was the boss of Peter Porker (aka Spider-Ham) on Larval Earth
A retired New York Police Department captain and the father of Gwen Stacy.
Spider-Woman is an Avenger and spy who got her powers from an experiment gone wrong. She has been an agent of S.H.I.E.L.D. and S.W.O.R.D., as well as a Private Investigator. Jessica was a crucial character in Marvel's Secret Invasion comic book event.
The very mention of his name makes lesser men tremble! The brilliant scientist whose iron mask conceals his scarred (but once handsome) face! Master of science and sorcery, Victor Von Doom is the monarch of Latveria, attempting the betterment of humanity through world conquest! Unequaled and unrivaled in every manner, Doctor Doom has had many conflicts with both earthly and cosmic super-beings, but he will always be known as the eternal nemesis of Reed Richards and his accursed Fantastic Four!
Doctor Octopus is a supervillain originating from Marvel Comics. A former nuclear physicist and atomic researcher, Otto Octavius' life changed forever when one of his experiments went horribly wrong involving his four mechanical appendages used to assist him in his experiments. From then on, Octavius soon after his initial encounter has become one of the most dangerous supervillains in the Marvel Universe.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
During an experiment, Dr. Curtis Connors accidentally turned himself into a ferocious reptilian monster who seeks to turn humans into lizards like himself. The Lizard is one of Spider-Man’s oldest and deadliest foes while ironically, his alter ego is a close friend and former teacher of Spidey’s alter ego, Peter Parker.
Flash frequently bullied Peter Parker but was actually Spider-Man's greatest fan. In time, Flash befriended Peter, became a decorated war hero, and eventually joined the Marvel superheroes as a symbiote host, first with Venom and then with Anti-Venom.
Peter Parker's aunt-by-marriage and one of the most important people in his life.
Editor-in-Chief of the Daily Bugle, and perhaps the best friend to J. Jonah Jameson.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Betty Brant started as a personal secretary at the Daily Bugle and later became a top reporter. Betty is also one of the many love interests of Peter Parker and ex-girlfriend of Flash Thompson
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