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Aftershock First confrontation: Spider-Girl #51.00 Aftershock is the daughter of Electro in Earth-982 |
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Apox First confrontation: Spider-Girl #47.00 The daughter of Peter Parker, the original Spider-Man, May "Mayday" Parker continues her father's legacy as The Amazing Spider-Girl of Earth-982 (MC2 Universe). |
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Black Tarantula First confrontation: Unknown Allegedly for over 700 years, the title of the Black Tarantula have been passed down from father to son. |
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Carnage First confrontation: Unknown Carnage is the result of a spawning of a separate extraterrestrial symbiote worn by Venom. Carnage bonded with serial killer Cletus Kasady, creating one of Spider-Man’s most murderous adversaries. |
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Carolyn Trainer First confrontation: Unknown Otto Octavius' apprentice, she took the title of her mentor after Ocatius' death, and has fought Spider-Man |
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Crazy Eight First confrontation: Unknown Leslie Shappe is the killer known as Crazy Eight who was known for dispatching shady, underworld types. |
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Darkdevil First confrontation: Spider-Girl #2.00 Although now friends, Darkdevil originally thought that Spidergirl was evil. |
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Deadspot First confrontation: The Amazing Spider-Girl #16.00 An assassin for hire that took a job to kill Spider-Girl. |
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Dragon King First confrontation: Spider-Girl #4.00 The daughter of Peter Parker, the original Spider-Man, May "Mayday" Parker continues her father's legacy as The Amazing Spider-Girl of Earth-982 (MC2 Universe). |
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Earthshaker First confrontation: Spider-Girl #21.00 The daughter of Peter Parker, the original Spider-Man, May "Mayday" Parker continues her father's legacy as The Amazing Spider-Girl of Earth-982 (MC2 Universe). |
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Funny Face First confrontation: Spider-Girl #22.00
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Fury The Goblin Queen First confrontation: Unknown Member of a crime family in South America, she is a constant foe of both Normie Osborn and Spider-Girl. She is in the MC2 universe. |
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Galactus First confrontation: Unknown She had to stop him in Last Planet Standing. |
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Hobgoblin First confrontation: Unknown The original Hobgoblin became a worthy heir of the goblin legacy. He set out to create his own identity rather than be just another Green Goblin clone. |
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Kaine First confrontation: Spider-Girl #14.00 Kaine was one of the Jackal's first Spider-Man clones. He was a failure however, and the genetic disfiguration would subsequently cause a bizzare mutation in the clone. |
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Killerwatt First confrontation: Spider-Girl #9.00 Killerwatt is a member of the Revengers. |
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Kingpin First confrontation: Unknown The self-proclaimed Kingpin of Crime. |
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Magneta First confrontation: Unknown Magenta has come into conflict with Spider-Girl. |
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Mr. Abnormal First confrontation: Spider-Girl #15.00 The daughter of Peter Parker, the original Spider-Man, May "Mayday" Parker continues her father's legacy as The Amazing Spider-Girl of Earth-982 (MC2 Universe). |
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Mr. Nobody First confrontation: Spider-Girl #1.00
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Normie Osborn First confrontation: Spider-Girl #0.00 Son of Norman Osborn and Liz Osborn. |
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Raptor First confrontation: Spider-Girl #18.00 Daughter of Blackie Drago in the MC2 timeline. |
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Spyral First confrontation: Spider-Girl #3.00
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Venom First confrontation: Unknown Venom is an alien symbiote with an intense hatred of Spider-Man. It has bonded with a number of different hosts who all share its hatred, most notable Eddie Brock and Mac Gargan AKA The Scorpion. |
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Wizard First confrontation: Unknown The daughter of Peter Parker, the original Spider-Man, May "Mayday" Parker continues her father's legacy as The Amazing Spider-Girl of Earth-982 (MC2 Universe). |





