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Mal is the Captain of the ship Serenity. He is a veteran of the Unification War against the Alliance, fighting with the Independents (or "Browncoats").
Zoë is the second in command of Serenity, and a long-time friend of Captain Reynolds.
Subjected to Alliance experiments, River escapes with the help of her brother, Simon. With an unstable psyche, she now lives on Serenity on the run from the Alliance control.
A former mercenary, Jayne Cobb is part of the crew aboard Serenity and is in charge of "Public Relations".
Simon Tam is the brother of River Tam and ships doctor aboard Serenity. He is a medical genius and has been constantly fleeing Alliance control since saving his sister from a government experiment.
Wash is Serenity's pilot. He is married to Zoë, despite Mal's initial objections.
Inara is a certified Companion who lived aboard Serenity. Complications due to her attraction to Captain Malcolm Reynolds caused Inara's decision to leave Serenity.
Kaylee is the exceptionally chipper and genius mechanic aboard the ship, Serenity.
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