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Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Spider-Woman is an Avenger and spy who got her powers from an experiment gone wrong. She has been an agent of S.H.I.E.L.D. and S.W.O.R.D., as well as a Private Investigator. Jessica was a crucial character in Marvel's Secret Invasion comic book event.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
Peter Parker's aunt-by-marriage and one of the most important people in his life.
A famous big game hunter, who became a mercenary and later, developed an intense obsession with restoring honor to his name. Kraven has been known as a major threat for Spider-Man and leaving a legacy during his demise.
Betty Brant started as a personal secretary at the Daily Bugle and later became a top reporter. Betty is also one of the many love interests of Peter Parker and ex-girlfriend of Flash Thompson
Dmitri Smerdyakov, AKA Chameleon, was first member of an inexperienced Spider-Man's rogue's gallery. The Chameleon is an elite spy and a master of disguise, using a variety of masks, technology, and other inventive techniques to flawless mimic the appearance and mannerisms of virtually anyone. Although he has been revealed to be the half-brother of Kraven The Hunter, the face behind his trade-mark white mask – worn even beneath his other masks – has never been seen.
Lindsay McCabe is an actress and is Spider-Woman's (Jessica Drew) best friend. She also spent time with Wolverine in Madripoor.
Julia Carpenter is the second heroine to take up the mantle of Spider-Woman, later changing her name to Arachne. After the events of the Grim Hunt she became the new Madame Web and is currently a watcher and guardian of the Spyders.
Currently going by Sepulchre, Jillian Woods was first known as Shadowoman.
The Void-Eater is a massive demon that fills the entirety of its own dimension. Its body appears to be a void with mouths and tentacles.
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