Sandman's enemies

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Absorbing Man
First confrontation: Unknown

An ultra-violent boxer gone criminal, after Loki bestowed powers on him, he teamed up with the Masters of Evil.

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Afterburner
First confrontation: Unknown

Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after a humiliating merge with Hydro-Man.

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Agatha Harkness
First confrontation: Unknown

Mystical Nanny and housekeeper.

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Betty Ross
First confrontation: Unknown

Sandman once transfused Betty Ross' blood with his own, turning her to glass.

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Crime-Buster
First confrontation: Unknown

Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after a humiliating merge with Hydro-Man.

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Crimebuster
First confrontation: Unknown

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Devos The Devastator
First confrontation: Unknown

Devos the Devastator's sole responsibility is to eliminate every life form that has any prospect of ever waging war.

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Doctor Octopus
First confrontation: Unknown

Dr Octopus’s abilities derive from his four steel tentacles. Attached to a harness encircling his lower chest and waist, each telepathically controlled, telescoping limb can move at speeds of up to 90 feet per second and strike with the force of a jackhammer. Once he was Otto Octavius, a brilliant and respected nuclear physicist, inventor and lecturer. But a freak laboratory accident exposed him to intense radioactivity, grafting the tentacles to his body and transforming him into a criminally insane megalomaniac. Since then, Doc Oc has dedicated his warped genius to building an empire of crime and eradicating his most hated foe: the Amazing Spider-Man.

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Doombots
First confrontation: Unknown

The Doombots are robots created by Doctor Doom.

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Eddie Brock
First confrontation: Silver Sable and the Wild Pack #18.00

Eddie Brock, a reporter for the Daily Globe, a rival paper to the Daily Bugle, was fired after incorrectly reporting the real identity of Sin-Eater. He received the alien Symbiote to become the first Venom. He is now the symbiote Anti-Venom

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Foreigner
First confrontation: Unknown

The Foreigner is a higly inteligent, assassin and occational mercernary who is also a of master of disguise. He has no powers but is in peak phisical condition.

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Hammer Harrison
First confrontation: Unknown

Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after a humiliating merge with Hydro-Man.

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Hulk
First confrontation: Unknown

Hulk and Sandman had some good battles, as this was a foe Hulk's raw power couldn't beat. Hulk still smashed him up though.

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Human Torch
First confrontation: Unknown

Johnny Storm is the Human Torch, a member of the Fantastic Four and brother to Sue Storm. Due to a space accident he can fly and manipulate fire, including turning his entire body into a fireball.

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Hydro-Man
First confrontation: Unknown

They were fighting, but the sand and water mixed together into a being of mud. They spent months sharing the same body. That's not fun, especially if you're a villian.

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Invisible Woman
First confrontation: Unknown

Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after a humiliating merge with Hydro-Man.

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Leecher
First confrontation: Unknown

Leader of Bio-Genes, can control emotions.

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Mali
First confrontation: Unknown

Memebr of Bio-Genes

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Mary Jane
First confrontation: Unknown

Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after a humiliating merge with Hydro-Man.

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Mattie Franklin
First confrontation: Unknown

Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after a humiliating merge with Hydro-Man.

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Montana
First confrontation: Unknown

Member of the Enforcers.

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Mr. Fantastic
First confrontation: Unknown

Reed Richards is Mr. Fantastic, leader of the Fantastic Four, loving husband of the Invisible Woman, mentor to the Human Torch, best friend to the Thing, and one of the smartest men in the Marvel Universe.

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Nova
First confrontation: Unknown

Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after a humiliating merge with Hydro-Man.

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Sandstorm
First confrontation: Unknown

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Snake
First confrontation: Unknown

Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after a humiliating merge with Hydro-Man.

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Songbird
First confrontation: Unknown

Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after a humiliating merge with Hydro-Man.

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Spider-Man
First confrontation: Unknown

Spider-Man was Sandman's first and most frequent enemy. He first beat Sandman by tricking him into turning all into sand, then sucking him into an industrial vacuum.