Supernatural is a TV show that began in 2005 on the network known as The WB. The show's life was in the balance when the network merged with another and became The CW. After two successful seasons on the air and a huge fan base developed, the creator Eric Kripke launched the comic. The comic series is a prequel to the show and is titled Supernatural: Origins.

Sam Winchester was born May 2, 1983 to John Winchester and Mary Winchester and has a brother four years his senior named Dean Winchester. In the comic series, Sam first appears as a baby and then by issue #2 he's about six years old. During this time Sam has not developed any of his weaponry or psychic powers but since the TV series shows us Sam in the future, those traits are part of his character since Mary's unusual death in their Lawrence, Kansas home.

Several six-month-old children across the country experienced the exact same demon encounter as Sam: a fire in their nursery and someone was killed by a yellow-eyed demon; in Sam's case it's his mother Mary. (The comic series to date has not disclosed this unusual supernatural activity as being a national event.) When Mary died, Sam's father John obsessed and entered into the supernatural lifestyle to hunt for her killer, the yellow-eyed demon. John couldn't trust anyone and felt the boys would simply not be safe with another family member.

Sam is the younger brother and though he often seen crying or feeling insecure, he actually is a very strong individual capable of surviving without his father's or big brother Dean's protection. Dean was not touched by magic and does not possess the psychic abilities that Sam has. It's uncertain how much of this will be seen in the comic.

In issue #2, John finally meets the mentor he needs to keep himself and the boys alive. Unfortunately it's not until a Hellhound kills Mary's brother Jacob who had been tracking John and the boys.