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Rose Thompson is the loving mother of Jessie Thompson and Flash Thompson and wife of Harrison Thompson. Although she cared for the children very much, she could not stop her husband's drinking and his violont outbursts after that, mostly towards their own children. Although Rose tried to keep the peace between the family, they mostly drifted apart after both Jessie and Flash had become adults. Rose was more recently kidnapped by Human Fly when villains targeted Flash's closest family, since he became the new superhero Agent Venom.

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