The original series was pretty good, as was the first half of Marc Spector: Moon Knight (the second half sucked), but I still think the 2006 run is my favourite (yes, including Down South!).
Word. Okay, yeah, the 2006 run pretty much slid down to mediocrity once Huston left the title but that first opening arc is still glorious. That's still one of the best character relaunches I've ever read in comics.