I just don't understand the whole "I don't want these amazing powers, I just want to be ordinary" mindeset. I can understand that he has been through a lot because of his mutation, but getting rid of it won't reverse what has happened to him, why would he want to give up near immortality for a chance to be a lonely and fragile human?
I think the idea is that if you live forever, you soon stop grasping on to things that are finite, and lose a fundamental aspect of being human. As little as we think about being "mortal", we do to an extent value periods of our lives, or bonds to other people, because we know they will come to an end. One of the strongest emotional reactions we have is to the notion that we won't get to experience a particular thing again, or at all. If you live forever, your experiences are all crushingly insignificant in the broader sense, and that's not necessarily something the human psyche - inherently prone to attachment - is capable of dealing with.
But I think it's an abstract philosophical subject that has turned into a pretty generic genre/storytelling trope - one that somehow has made it more difficult to relate to than it actually is. I feel similarly about the trope of "not turning into your parent". "You're not your father!" and so on. It permeates all fiction, and I can't even count the times where it just falls flat, when it's actually a deeply relateable theme. You don't need a super villain/vampire/monster mother or father to identify aspects of their personalities that you dislike, but share, and to an extent fight to overcome.
As for this movie, I think this trailer makes the problem more clear than previous trailers have. We just don't really know what it's about - what the actual meat of the story is. This trailer sets it up in a more linear way than the rest have, and you can kind of follow the thread to where it just abruptly ends, and they cue CG blob samurai and train fights. It makes it look like it's literally written as a set up where he's moping around, loses powers, and "then there's some fighting". That's hard for ANYONE to be excited about. Unless you just wanna see Wolverine stab things, which seemed to be the entire basis for Origins, basically.