1. Supreme Power
Similar origin to Superman, but as the story goes on it gets much different and better. The main character Mark Milton crash landed on Earth and was raised by the government to love and fight for the USA. Things start getting interesting when he discovers that he was lied to his entire life and now he wants revenge on those people.
2. Sweet Tooth
It is a post-apocalyptic world where children are being born half human, half animal and Gus (Sweet Tooth) is the key to discovering how it all began. Written and drawn by the same person, Jeff Lemire, it is one of the most beautiful books out there. The art style is very unique, but in combination with the story, it all works perfectly. Another reason I am enjoying this book is because of the way you care about the characters and their relationships. I've never cared about fictional characters as much as I do in Sweet Tooth.
A creature, Annihilus, from another universe has come to destroy everything and everyone in our universe. Only the elite cosmic characters stand a chance at stopping him. The story is broken into several parts. First is the Prologue, then there are 4 different miniseries; Annihilation: Super-Skrull, Nova, Ronan, and the Silver Surfer, lastly there is a 6 issue miniseries which is the finale. This was a great series that forced heroes and villains to work together, but is it enough?
4. Astonishing X-Men
This was the first series I really started collecting and it's one of my favorites. Written by Joss Whedon and drawn by John Cassaday, it has a great story and dialogue accurate to the characters, with some humor thrown in there. The art is very clean and looks really good. I would only recommend issues 1-24 and Giant Size X-Men #1 which is the finale. After that, the creative team changed and the series just got weird.
5. Animal Man
Written by one of my favorite authors, Jeff Lemire, and drawn by Travel Foreman, this is an extremely entertaining, deep and unique book. An interesting hero, with an amazing ability and a family he lives for makes this one of the best books in print.