Jeff Goldblum as Reed Richards
Amanda Tapping as Sue Storm
Jesse Spencer as Jonny Storm
Micheal Chiklis again as The Thing
and Hugo Weaving as Victor von Doom
since the reboot doesn't have to be an origin story like what the second hulk movie did. then we can use older actors.
I reckon it will be an origin story but i HOPE it isn't. And i think Hugo won't play another comic book character for a while after what he said about being Red Skull.