Spider-Man stops at Omega Red without question guys. His deathspores were enough to drop an entire team of X-Men including Colossus and Ms. Marvel empowered Rogue quickly and succinctly.
Cyber could also prove problematic. His strength levels should enable him to deal with the webbing (easily a 10 tonner) and 90% of his body is impervious to harm. I don't know how strong his jaw is, so Spider-Man might be able to KO him before Cyber lands a decisive blow with his adamantium laced, and poisoned claws. One hit though, actually, one little nick with those claws, and Parker's toast. Let's not forget, Cyber trained Daken in part, so his hand to hand is top tier (or very close to it).
I'd go so far as to say even Mister X is a tough, tough fight for Spider-Man to get clear of simply due to the nature of each ones strengths and weaknesses. Mister X literally maps onto his opponent's brainwaves (he does not simply read their minds) and his reflexes react automatically to said brainwaves. Coupled with the fact he's mastered every martial form on earth, along with those of both Kree and Sh'itar, and has shown the knockout power to take down Wovlerine ... he is potentially too much for Parker. If any top tier has what it takes to tag Parker, it's Mister X due to his mutant power.
I'd say the webbing is the real problem for Mister X. Though, he does carry his twin katanas as standard gear, that could potentially deal with parker's webbing ... he has twirled them around fast enough to deflect automatic gunfire from Black Widow. Debatable.
Irregardless, he definitely stops at Red.
this seems more or less correct to me. i think Spidey LOSES to Omega Red 7/10 times. I do think he would beat Cyber but it would be tight. I wouldn't be shocked if it went the other way. I say Spidey WINS against Cyber 7/10 times, Mister X 7/10 times and beats everyone else 9/10 times at least.
But Omega Red is too much.
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