This is a pretty loaded question, and as I don't read all industries' comics, I can't justifiably vote. Each company, determined by industry traits, has been guilty of portraying women in substandard ways, and will be quick to jump on to the next trend without a beat.
It's hard for me to pick just one favourite Doom story, however, Emperor Doom is definitely a classic. Doom finally achieves his goal of world domination, utilizing the powers of the Purple Man to enslave the world and its heroes. I won't spoil the ending, but it features a very interesting twist. :)