SpOck, and only SpOck. Why? While Goblin has his powers and the capability of flight Red himself has Death Spores, "The death spores result in the weakness or death of humans in his immediate vicinity. The severity of the effect is based on the endurance, health, and relative proximity of the victims. The spores are fatal to ordinary humans within seconds, though some superhumanly powered beings can withstand exposure to them for extended periods of time" (thanks Wiki) while his other powers include "superhuman strength, speed, stamina, durability, agility, and reflexes" (Wiki). This alone leaves Ol' Goblin out of commission. The next thing is SpOck. Smart and lethal. SpOck will be able to use the brute force of both characters, Red and Wolverine, against them not and not going toe to toe "all out brawl" with the two of them. SpOck has his Spider eyes and he could care less if Goblin dies, it is really just one less thing for him to do himself.
Again-SpOck for the win Folks!