Just a few thing I've learned that may or may not help you
Juggernaut Teams: Bruisers: Juggernaut, Hulk, Thing, Venom, Ms. Marvel, Luke Cage X-men (should be obvious)
Bishop boss fight: Part 1 fight Bishop until he runs low on health and retreats to recharge at the power generator, then quickly run behind the generator and attack the yellow lit tubes, they will turn red and after enough damage will explode, the generator will then explode in Bishops face making the rest of phase 1 of this battle simple.
Part 2: Three generators are now in play, as well as an electrical field overhead in the center of the battlefield, fight Bishop in the same way as before with one minor change in strategy, Bishop now unleashes an attack that sucks in all your heroes and throws them across the screen, this is easily spotted when the ground beneath Bishop glows blue, at which point get away from him as fast as you can. Weaken Bishop until he runs to a generator to recharge, then quickly move to one he isnt recharging at: Deadpool is great for this as his teleportation and jumping sword slash make this pretty simple: Teleport behind the first generator Bishop is not recharging at and attack it quickly, then teleport to the sewcond generator Bishop is not recharging at and repeat, the quicker you pull this off the less health Bishop recovers. (targeted fusions are the best to use on Bishop while he is actively fighting you)
Part 3: Bishop will move into the center and try to recharge, this is your chance to end the fight: If you followed my advice and are using Deadpool, simply double jump to trigger your teleportation to quickly get behind each generator and use your jumping sword slash (RT+B on an XBOX360 controller) to quickly take out all three generators, timed correctly this strategy will turn Bishop from one of the games most formidable bosses to one of it's easiest
The never run out of health trick: When your characters have some breathing room and are not being attacked, switch characters low on health out for Wolverine or Deadpool, the healing factors of these characters will recover whatever slot they are assigned to fully, and you can do it as often as you need to!