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Carnage First confrontation: Unknown Carnage is the result of a spawning of a separate extraterrestrial symbiote worn by Venom. Carnage bonded with serial killer Cletus Kasady, creating one of Spider-Man’s most murderous adversaries. |
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Chameleon First confrontation: Unknown Mary Jane once defeated the Chameleon by knocking him out with a baseball bat. This would later be referred to as an embarrassing moment for the Chameleon. |
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Doctor Octopus First confrontation: Unknown Dr Octopus’s abilities derive from his four steel tentacles. Attached to a harness encircling his lower chest and waist, each telepathically controlled, telescoping limb can move at speeds of up to 90 feet per second and strike with the force of a jackhammer. Once he was Otto Octavius, a brilliant and respected nuclear physicist, inventor and lecturer. But a freak laboratory accident exposed him to intense radioactivity, grafting the tentacles to his body and transforming him into a criminally insane megalomaniac. Since then, Doc Oc has dedicated his warped genius to building an empire of crime and eradicating his most hated foe: the Amazing Spider-Man. |
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Eddie Brock First confrontation: The Amazing Spider-Man #299.00 Eddie Brock, a reporter for the Daily Bugle, received the alien Symbiote to become the first Venom |
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Green Goblin First confrontation: Unknown Perhaps Spider-Man's deadliest and most dangerous villain. There's no stopping what this madman will do to get what he wants. |
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Gwen Stacy First confrontation: Unknown Mary Jane competed against Gwen for Peter's love. Gwen won the competition, but with her tragic death, Peter ended up marrying MJ. |
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Lizard First confrontation: Unknown MJ is the wife of Peter Parker (Spider-Man). She is the 4th love interest in Parker's life behind Liz Allan, Betty Brant, and Gwen Stacy. She is also a professional model and actress. |
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Pandara First confrontation: Unknown
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Sandman First confrontation: Unknown Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after a humiliating merge with Hydro-Man. |
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Scorpion First confrontation: Unknown
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Spider-Slayer First confrontation: Unknown Originally created by J. Jonah Jameson, they almost killed Mary Jane the first time Spider-Man confronted them. Which was the first time he realized that he was putting Mary Janes' life in danger by being with her. |
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Spot First confrontation: Unknown MJ is the wife of Peter Parker (Spider-Man). She is the 4th love interest in Parker's life behind Liz Allan, Betty Brant, and Gwen Stacy. She is also a professional model and actress. |
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The Jackal First confrontation: Unknown The Jackal tortures the lives of the Parkers during the Clone Saga. Mary Jane also became pregnant during this time, although it was retconned to never happened. |
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Venom First confrontation: The Amazing Spider-Man #299.00 Venom is an alien symbiote with an intense hatred of Spider-Man. It has bonded with a number of different hosts who all share its hatred, most notable Eddie Brock and Mac Gargan AKA The Scorpion. |
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