Dr. Strange and Clea, his disciple/girlfriend, are waiting in a New York subway station where a blond girl is playing some music on her harmonica. As she finishes, a young tough comes up and grabs her harmonica, attempting to play it. She grabs for it, but falls/ is knocked onto the tracks. As a train approaches and Dr. Strange reaches to save her, she begs him to ignore her and grab the harmonica, which he does. The train hits the girl, who promptly explodes into a shower of odd fireworks which settle onto all present. Puzzled, Dr. Strange and Clea take the harmonica (inscibed with the word "Celestia") and return to Strange's Sanctum Sanctorum.
In the Baxter Building, a snoozing Ben is awakened by a late night phone call from a Mrs. Coogan, who he knew in childhood. Hopping in the Fantasticar, he heads to her home on Yancy Street. We soon learn that her grandson had been one of those in the subway when the girl 'exploded'. Ben soon leaves, not really knowing what to do about it.
Dr. Strange determines that the exploding girl was a manifestation of 'destiny', and that as such all those people she interacted with in the subway are about to be strongly affected in some way. Doc sets out to find all those people before they're destroyed by their redirected destinies. He runs into Ben, and the two shortly realize that they're on the same case...
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