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Provence, 1550. After being plagued by unexplained visions, a doctor starts to write a series of blocks that contain dark prophecies, and his name is Michel de Notre-Dame, but will go down in history as "Nostradamus". Rome, 2011. Martin Mystere visits a scholar of his knowledge, Professor Mercalli, who has discovered what may be an unknown text by Nostradamus. Mercalli, however, dies in unclear circumstances, and Martin is forced to seek help from an old acquaintance, fascinating Inspector Nadia De Pascali to discover what secret lies behind what has been dubbed "The source of the future".