When Richard Stanton's daughter is kidnapped, he uses his acting skill to create a new persona, and elderly lady called Madame Fatal.
In his guise as Madame Fatal, Richard found he was underestimated by his daughter's kidnappers. After effecting her rescue, he decided to adopt the identity and fight for justice, becoming the first transvestite hero.
Stanton, lives alone with his pet parrot Hamlet. Madame Fatal is one of the many heroes of the time who fought crime with no more than their native wits and skill.
Madame Fatal goes under cover to protect Darnell Caldecott from an assassination attempt. Caldecott's wife goes missing a 2 days later. Vigilante agrees to help The Shade find Grace Caldecott. Vigilante locates Grace Caldecott who is in league with The Nazis. She wants Caldecott and take his fortune while The Nazi's take his experimental plane, the Z44. Madame Fatal and The Shade locate Darnell Caldecott on his plane, now a hostage to the Nazi's. Madame Fatal knocks out a group of the sabatours while The Shade uses his shadow power to knock the rest out of the plane. Shade gives the location of Dr. Prowl, an old adversary, who has kidnapped his daughterand held her captive for 11 years.
"She" appeared in the first twenty-two issues of Crack Comics. After the line was bought out by DC Comics, Madame Fatal disappeared and was never seen again. The only other reference to "her" is found at the funeral of Sandman at Valhalla Cemetary in JSA #1. There, Wildcat is heard wondering if his own funeral will be like the time they buried Madame Fatal here and no one turned up for the funeral but the touring cast of La Cage Aux Folles. This may make reference to the character dying in the DC canon or a comic book death.
Madame Fatal's chief foe was the Jester, not to be confused with the Golden Age superhero with the same name.
Some believe that Madame Fatal may have been the first out comics character. Richard Stanton mirrored many of the stereotypes found in the 1940's (living alone, theatre experience, and cross-dressing), but none of these are conclusive.