Lizard

This reptilian monster has often fought Spider-Man in his quest to have the world be ruled by genetically enhanced reptiles. Black Cat fought, and nearly killed, the Lizard when heroes and villains alike who possessed animal based powers went feral!

Former employer and pain the in ass of Spider-man. He is the publisher and editor-in-chief of the Daily Bugle, a New York newspaper.

Small time thug who gained super-strength, and eventually terminal illness, through abusing an experimental horse steroid.

Morbius faught Lizard in Long Island.

A sword-master in peak human physical condition, martial arts expert, as well as knowledge and experience of fighting the supernatural.

Dr. Curt Conners was scientist studying reptilian limb regeneration, in an attempt to regrow his own arm, which he lost during the war. When he tested the experimental formula on himself, he turned into The Lizard.

Warrant was hired to capture or kill the Lizard For a time it seemed Warrant had killed The Lizard in a battle between the two and Spider-Man