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Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Doctor Octopus is a supervillain originating from Marvel Comics. A former nuclear physicist and atomic researcher, Otto Octavius' life changed forever when one of his experiments went horribly wrong involving his four mechanical appendages used to assist him in his experiments. From then on, Octavius soon after his initial encounter has become one of the most dangerous supervillains in the Marvel Universe.
A career criminal, the man known as Rhino has incredible strength and durability. A long-time enemy of Spider-Man and the Incredible Hulk, Rhino isn't particularly malicious, and has tried on various occasions to leave behind his life of crime, but always seems to slide back into old habits.
Swindled by his business partner out of his equal share of the profits from their company, Adrian Toomes set out for revenge by using a flying harness of his own design. He has however, met defeat several times at the hands of his arch-nemesis, The Amazing Spider-Man.
Growing tired of his mechanic job, Abe Jenkins created a suit of armor and became the Beetle. Originally a criminal, he changed his ways as a member of the Thunderbolts, Taking the name MACH-1. Abe became a mainstay of the group and achieved legitimacy as a superhero. As he's upgraded his armor, he's changed his name to reflect the version of his armor, currently MACH-X.
Former pro baseball player who became a known criminal as the Boomerang. After fighting towards some semblance of redemption as a member of the Thunderbolts, he lead the seventh incarnation of the Sinister Six.
A former assistant to Curt Connors, Vincent Stegron used stegosaurus DNA to augment his body.
A hit man with an angle, a costumed villain with the solution, he is The Answer!
The former wife of the supervillain Ringer, Leila Davis began her own criminal career as Hardshell before eventually adopting the Beetle guise when the original Beetle became MACH-I.
Elias Hargrove is Dr. Octopus' cousin.
A former Nazi scientist, von Meyer's expertise in cosmic radiation allowed him to mutate a colony of bees, thus becoming Swarm. As Swarm, von Meyer's body is completely made of bees.
Anthony Davis was the first super-villain known as Ringer. After his untimely near-death at the hands of the Scourge of the Underworld, he was rebuilt as the cyborg Strikeback.
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