Origin

Little is known about the mutant named Layla Miller. She first appeared during the House of M as the only person other than Wolverine, the Scarlet Witch, and Quicksilver to have any knowledge of the true past. During this time she was able to use her abilities to "unlock" their true memories so that they may remember the truth. By doing this to a number of key heroes, she played an important role in destroying the House of M.

House of M Layla

During the House of M Doctor Strange suggested that the Scarlet Witch may have created Layla for this express purpose. It is unknown if this is the case because while she remained after M-Day, the Scarlet Witch may have added her into the current (and only slightly altered) reality.

X-Factor Investigations

After M-Day, Jamie Madrox reformed X-Factor in Mutant Town. In the first issue, Layla just appears in the HQ and begins organizing the files, just telling the members "I'm Layla Miller. I know stuff". Layla handed Rictor a coupon off gas, and there was an incedent at a gas station, which did help convince him to join X-Factor. She tells the team about incoming phone calls and and a client who's entering. She fixes the bath for M, and when a Singularity Investigations employee goes to kill Rictor (believing him to be the cause of their problems when it was Layla) she killed him by electrocuting him (she did admit to him that she's there at X-Factor because she has to stop them from finding out the truth behind the Decimation). She then orders a special deliverer to take him back to Singularity, with the message to back off.

When Siryn was attacked, Rictor instantly blamed Layla for not telling them about it (although Strong Guy threatened him at first for making this accusation, showing that he's some what protective of her). Layla walks outside, and after talking to Wolfsbane, a woman from the orphanage Layla lives at pulls up, telling Wolfsbane she run away. The woman says that Layla was having some trouble before, because apparantly she was a mutant who could breathe fire and had horns. The woman takes Layla back to the orphanage (in a quick flashback we see that her father nicknamed her "Butterfly"). Wolfsbane and Madrox decide to go visit Layla, but the woman refuses to let them see her. Wolfsbane sniffs her out, only to find Layla covered in bruises. After Wolfsbane scares the other kids, Layla reveals why she couldn't tell them about Siryn getting attacked: she'd be killed if she did. Layla compared herself to a butterfly in the "Chaos Theory", and when she had to, she flapped her wings. Wolfsbane and Madrox try to adopt Layla, but are unable to, because the X-Factor organization are technically not a family, but she said that with all the work she has going on, if a child slipped through the cracks, she wouldn't be able to file a report.

When Quicksilver comes to town, Layla tries to get him killed by getting ex-mutants to change him, but because of his relation to the Scarlet Witch messed with her powers. She then journey's with the team to confront the X-Men, and Wolverine recognies her. We also see that Layla reads at the bottom of the steps, and that she eats "Cherioes" with water and yogurt.

When the team launch an attack against Singularity Investigations, Layla frees their hostage after causing a traffic jam slowing down the van she's in.

Note - For a while, Layla was unable to see anything happening to Strong Guy, although this most probably was because of him being hypnotized by Singularity.

Note - Layla hinted that she would get married to Madrox in the future.

"I'm Layla Miller. I know stuff."

When the team go to see Doc Samson, Layla lay upside down on the sofa, saying she found the world looke more interesting that way. After making a referance to Star Trek, she compares herself to pawn, because she's just another person.

Later, Layla forces M and Siryn to be friends. When Nicole is brought back, Layla becomes quite annoyed when she didn't see her joining. Layla gives the group instructions where to be to find X-Cell, and later during the final confrontation, Layla shows several members of X-Cell a recording proving to them that it wasn't the goverment who were behind the Decimation, but rather the Scarlet Witch. Quicksilver was about to kill her but she was saved by Rictor.

Nicole later finds a pregnancy test, but Layla doesn't know who's regnant. She takes the test to a bridge in the middle of a park, and begins to wonder. Nicole shows up, and brutally attacks her with a rock, hitting her over the head and knocking her into the river. Layla nearly dies, but is saved by Quicksilver, because he believes that he has to kill her. She manages to escape from Quicksilver, and warns Madrox about what Nicole said, that Huber wanted her dead, and Jamie knows exactly who she's on about.

Layla goes to take the subway, but is followed by Nicole. Nicole goes to push Layla in front of train, but Layla picks a penny up and Nicole trips over her and falls in front of the moving train, revealing her to be a robot.

*Note - Layla was unable to see anything revolving around Nicole with her abilities because the Isolationist built in a "chaotic randomizing generator" to her body. It is unknown why the Isolationist himself was invisible to her powers.*

Messiah Complex

Layla has currently snuck in to the future with a dupe of Multiple Man (Jamie Madrox) in order to find out what has happened along that timeline. She got there by jumping on the time machine just as Jamie was about to travel. They have found out that a war between humans and mutants has happened, with a mutant being responsible for the beginning of it. All the mutants are currently locked away in an outdoor prison, watched over by Sentinels. Layla's powers are not working in the future however and she is doing research by means such as libraries. When she and Jamie attacked some guards at the camp to try and gain information, more troops were instantly alerted as soon as they uttered the word 'mutant' due to the government clampdown. Their scanners detected only the mutant 'X' gene in Jamie but as they took him away, Layla admitted that she was a mutant herself to Jamie's disbelief.

Layla After Being Balded And Marked

After the two of them are taken away, shaved, and branded with the "M" mark, they are both put in the concentration camp. There they find Lucas Bishop as a child, and ask him what happened. He just tells them that if he could, he'd go back and kill the mutant that made this happen. Jamie and Layla realises what this means, and before Jamie (well the dupe as you know) can do anything, she throws a stolen grenade at him, killing him. Just before he's killed, she hesitates, and before finishing her slogan, she changes her surname from Miller to Madrox. Prime Jamie wakes up and warns the others, leaving Layla stranded in the future.

Before the Future: The New Howling Commandoes

Recently Daisy Johnson approached Layla to become a member of her new superhero team. Layla appeared several years older than before and she told Daisy she could not go with her as "it wouldn't work out". She did tell Daisy that she would survive the coming crisis, but the mutants needed Layla much more than she did.

Powers

Layla has demonstrated telepathic abilities during the House of M, but has not since M-Day. Her precognition has not been fully explored, but seems to be able to perceive almost any event's outcome long enough before it occurs to casually (and generally cryptically) warn people if she feels it is warranted. Her abilities were shown to have limits when she was surprised to learn that her abilities to understand future events are hindered when dealing with mutants that Quicksilver, mutants he has re-powered, and Damian Tryp.

Several people have demonstrated that they've been invisible to her powers. Strong Guy was most probably invisible to her powers for a while because he was hypnotized, and Nicole was because the Isolationist built her with a "chaotic randomizing generator".

Although Layla has claimed that she once had horns and could breathe fire, she may not have meant for this to be taken literally, as she is explaining to Jamie Madrox that she was an outcast and treated badly by the other children in the orphanage.

Layla has , for lack of a better term, danger sense, because she is able to see things/attacks that will happen, allowing them to evade them (http://www.comicvine.com/comic/x-factor/18109/114395/&i=24131).