Miles Warren was a professor at Empire State University.. He later developed a fondness of Gwen Stacy who was a student of his. After she was killed by Green Goblin, Miles blamed Spider-Man instead.

From then on he became the Jackal after putting Jackal DNA in his body.

Jackal is also responsible for the creation of Carrion, as well as the two Spider-Man clones Scarlet Spider and the deformed Kaine. Miles was born into a family that had a love for science. His brother was a teacher for Peter Parker but, Miles wanted to be more than that. After he got his ph.d in biochemistry he went and joined the High Evolutionary so he could experiment. He would try to turn animals into humans. Most of his subjects never lost their animal appearance. One day Miles created two men that looked almost human. The High Evolutionary started to have arguments with Miles including when the two men started to worship him. When miles made a jackal into a human and which it had a crazy personality it ran away. The High Evolutionary would then banish Miles from the High Evolutionary. After that he went and married a girl named Monica where he had two children. But, after spending too much with his research his wife left him. Later Miles finds out that the Jackal he had created became envious and killed Miles wife. He blamed High Evolutionary for the action and told them that he would turn animals into humans. Every summer he would go to the High Evolutionary. He resided in Manhattan where he became a Professor. One day he saw Gwen Stacy and fell in love with her. Confused with his own feelings he considered her like the daughter he never had. Miles had Gwen and Peter in his class. He then had a lady collect cell samples from each of his students. He tried useing the cells to turn the two men he had altered before into humans. But, the serum ended up turning the two men into living corpses so he killed them. He would then work more on cloning. He invited Peter Parker to show him a project he had been working on and Peter decided to take Gwen along. Later, the Green Goblin attacked and killed Gwen and Green Goblin was thought to be dead. Miles was so sad he took cells from Peter and Gwen and made clones of them. During the process he killed a man. But, he became so disturbed of what he had done he made himself believe someone else did it. When he was talking about Jackals during class he thought of the Jackal man he created. SO thinking that it was spidermans fault for Gwens death he made a green suit with extractable claws and other gadgets and called himself the Jackal. Now he was going to take revenge on Spiderman he then asked Punisher to kill him. But, this attempt failed. Miles would then try a bunch of other schemes that ended up failing. The Jackal would spy on Parker when one day he saw Peter tossing a spiderman suit aside. He later wanted to make sure it was Peter and tricked him into having to change into his Spiderman suit while Miles was watching him. Later, Norman Osborne was still alive helped Miles make clones of Peter. When they finally made one it started to disentergrate and it ran away calling himself Kaine. Miles would then create machines that would control the clones he had made that were not messed up. One day when Miles was createing a clone to destroy the human race it woke up to early and so it became Carrion. Miles had thought he had killed Spiderman after a big explosion. Spiderman was still alive though and went into hiding. Much later Miles put himself in a genetic regeneration chamber which shaped his body into the look of the Jackal man he had created. He then created many clones and went crazy. When Miles went on a quest to kill all human kind. He would kill all humans and replace them with clones. But, when a Gwen Stacy clone was falling off a building Miles remebered his love for her and tried to save her only falling to his death. It has yet to be revealed whether if it was just a clone who died. But, for now Miles alleged son has become the new Jackal.