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Isaiah 6:2 is a member of the Rapture, a group of superheroes working for televangelist Reverend Skagg. Advised by a disguised Shapeshifter he made a plea to his viewers for volunteers with police or military backgrounds to come forward and join his holy crusade. Twelve hundred volunteers came forward, and Skagg tortured them to death, each in a unique and brutal manner; as Shapeshifter had expected, the violent deaths attracted the Shadowspear, a storm of magical energy previously assembled by Shapeshifter's former ally Saker, and its energies resurrected six of the twelve hundred as undead superhumans, the Rapture, naming each individual for passages in the Bible.
In the winged Isaiah 6:2's case, her passage reads "Above him were seraphim, each with six wings: With two wings they covered their faces, with two they covered their feet, and with two they were flying."
Isaiah's only known power was her wings which allowed her to fly. After initially establishing a reputation doing good deeds, the Rapture ambushed the Elementals away from public view, as Skagg viewed that hero team as abominations serving Satan. Isaiah used her aerial abilities to her advantage, luring other fliers in closer and dive bombing those who could not fly, but was accidentally killed by Monolith.